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WormBase Tree Display for Gene: WBGene00020251

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Name Class

WBGene00020251SMapS_parentSequenceT05C1
IdentityVersion3
NameCGC_namecamt-1Person_evidenceWBPerson260
Sequence_nameT05C1.4
Molecular_nameT05C1.4a
T05C1.4a.1
CE33443
T05C1.4b
CE33444
T05C1.4c
CE32207
T05C1.4b.1
T05C1.4c.1
Other_nameCELE_T05C1.4Accession_evidenceNDBBX284602
Public_namecamt-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:02WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
221 Dec 2004 16:07:27WBPerson2970EventAcquires_mergeWBGene00043487
322 Sep 2011 11:35:55WBPerson2970Name_changeCGC_namecamt-1
Acquires_mergeWBGene00043487
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcamt
Allele (251)
StrainWBStrain00031462
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (39)
Structured_descriptionConcise_descriptionT05C1.4 encodes, by alternative splicing, two members of the CAMTAfamily of calmodulin-binding transcriptional activators that arerequired for embryonic development; CAMTA proteins are conserved inanimals and plants but absent from unicellular eukaryotes, and may thusrepresent a transcriptional activator specific to multicellularorganisms; the common organization of CAMTA proteins is to have twoN-terminal DNA-binding domains (CG-1 and TIG), followed by two ankyrinrepeats, and then two or more calmodulin-binding IQ repeats; the domainorganization of T05C1.4 somewhat resembles that of NF-AT, anon-canonical Wnt transcription factor (TF) in other organisms than C.elegans.Paper_evidenceWBPaper00004651
WBPaper00013032
Curator_confirmedWBPerson567
Date_last_updated11 Dec 2006 00:00:00
Automated_descriptionEnables chromatin binding activity. Involved in positive chemotaxis; positive regulation of transcription by RNA polymerase II; and response to oxygen levels. Located in nucleus. Part of chromatin. Human ortholog(s) of this gene implicated in nonprogressive cerebellar ataxia with mental retardation. Is an ortholog of human CAMTA2 (calmodulin binding transcription activator 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050998Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18806)
Molecular_infoCorresponding_CDST05C1.4a
T05C1.4b
T05C1.4c
Corresponding_transcriptT05C1.4a.1
T05C1.4b.1
T05C1.4c.1
Other_sequence (42)
Associated_feature (17)
Transcription_factorWBTranscriptionFactor000241
Experimental_infoRNAi_resultWBRNAi00001809Inferred_automaticallyRNAi_primary
WBRNAi00052485Inferred_automaticallyRNAi_primary
WBRNAi00018214Inferred_automaticallyRNAi_primary
WBRNAi00103506Inferred_automaticallyRNAi_primary
WBRNAi00035188Inferred_automaticallyRNAi_primary
WBRNAi00052484Inferred_automaticallyRNAi_primary
WBRNAi00018216Inferred_automaticallyRNAi_primary
Expr_patternExpr1016646
Expr1038816
Expr1156109
Expr2009713
Expr2027952
Drives_constructWBCnstr00025265
Construct_productWBCnstr00022560
WBCnstr00025265
Regulate_expr_clusterWBPaper00061902:camt-1(ok515)_regulated_AFD
WBPaper00061902:camt-1(ok515)_regulated_BAG
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00061902:CAMT-1_interacting
Microarray_results (35)
Expression_cluster (120)
Interaction (12)
Map_infoMapIIPosition-4.31047Error0.010436
PositivePositive_cloneT05C1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00033395
WBPaper00038491
WBPaper00048493
WBPaper00055090
WBPaper00061738
WBPaper00061902
WBPaper00063687
WBPaper00065331
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene