WormBase Tree Display for Gene: WBGene00020146

WBGene00020146 SMap: S_parent: Sequence: T01C8
  Identity: Version: 2
    Name: CGC_name: got-1.2 Person_evidence: WBPerson151
            WBPerson14155
      Sequence_name: T01C8.5
      Molecular_name: T01C8.5
        T01C8.5.1
        CE07462
      Other_name: got-1 Paper_evidence: WBPaper00054184
        CELE_T01C8.5 Accession_evidence: NDB BX284606
      Public_name: got-1.2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 31 Aug 2011 09:11:34 WBPerson2970 Name_change: CGC_name: got-1.2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: got
    Allele (28)
    RNASeq_FPKM (74)
    GO_annotation (20)
    Ortholog (44)
    Paralog: WBGene00015771 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
      WBGene00015778 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016652 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Enables L-aspartate:2-oxoglutarate aminotransferase activity. Involved in positive regulation of glutamate metabolic process. Located in cytoplasm. Expressed in head; neurons; and tail. Human ortholog(s) of this gene implicated in several diseases, including amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Is an ortholog of human GOT1 (glutamic-oxaloacetic transaminase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9120 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4432)
      DOID:332 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4432)
      DOID:3498 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4432)
      DOID:224 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4432)
  Molecular_info: Corresponding_CDS: T01C8.5
    Corresponding_transcript: T01C8.5.1
    Other_sequence (69)
    Associated_feature: WBsf1008677
      WBsf1024878
      WBsf238407
      WBsf238408
  Experimental_info: RNAi_result: WBRNAi00033441 Inferred_automatically: RNAi_primary
      WBRNAi00027448 Inferred_automatically: RNAi_primary
      WBRNAi00026146 Inferred_automatically: RNAi_primary
      WBRNAi00026145 Inferred_automatically: RNAi_primary
      WBRNAi00017961 Inferred_automatically: RNAi_primary
      WBRNAi00052112 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1618
      Expr6562
      Expr13712
      Expr1012201
      Expr1038762
      Expr1155745
      Expr2012178
      Expr2030414
    Drives_construct: WBCnstr00004361
      WBCnstr00025344
    Construct_product: WBCnstr00025344
    Microarray_results (21)
    Expression_cluster (183)
    Interaction (53)
  Map_info: Map: X Position: 24.0611
    Positive: Positive_clone: T01C8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00040475
    WBPaper00049828
    WBPaper00055090
    WBPaper00062625
    WBPaper00065140
    WBPaper00065331
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene