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WormBase Tree Display for Gene: WBGene00019820

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Name Class

WBGene00019820SMapS_parentSequenceR02D3
IdentityVersion2
NameCGC_namecogc-8Paper_evidenceWBPaper00026979
Person_evidenceWBPerson449
Sequence_nameR02D3.2
Molecular_nameR02D3.2
R02D3.2.1
CE18096
Other_nameCELE_R02D3.2Accession_evidenceNDBBX284604
Public_namecogc-8
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:02WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
216 Jan 2006 17:12:59WBPerson2970Name_changeCGC_namecogc-8
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcogc
Allele (41)
RNASeq_FPKM (74)
GO_annotation00032578
00032579
00032580
00032581
00032582
00032583
00032584
00032585
00124585
Ortholog (52)
Structured_descriptionConcise_descriptioncogc-8 encodes an ortholog of mammalian COG-8, a subunit of lobe B ofthe conserved oligomeric Golgi complex (COGC); COGC-8 is weakly requiredfor normal gonadal distal tip cell migration, a process that alsorequires seven other orthologs of COGC subunits; like other lobe Bsubunits in both C. elegans and S. cerevisiae, COGC-8 is only partiallyrequired for normal function, while lobe A subunits are stronglyrequired in either worms or yeast.Paper_evidenceWBPaper00026979
WBPaper00028363
WBPaper00028599
WBPaper00028603
Curator_confirmedWBPerson567
Date_last_updated25 Oct 2006 00:00:00
Automated_descriptionInvolved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIh. Is an ortholog of human COG8 (component of oligomeric golgi complex 8).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070260Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18623)
Molecular_infoCorresponding_CDSR02D3.2
Corresponding_transcriptR02D3.2.1
Other_sequence (13)
Associated_featureWBsf645745
WBsf659867
WBsf995108
WBsf227817
WBsf227818
WBsf227819
Experimental_infoRNAi_resultWBRNAi00064306Inferred_automaticallyRNAi_primary
WBRNAi00017313Inferred_automaticallyRNAi_primary
WBRNAi00099110Inferred_automaticallyRNAi_primary
WBRNAi00034527Inferred_automaticallyRNAi_primary
WBRNAi00051123Inferred_automaticallyRNAi_primary
Expr_patternExpr1024523
Expr1038587
Expr1154832
Expr2010296
Expr2028538
Drives_constructWBCnstr00025571
Construct_productWBCnstr00025571
Microarray_results (21)
Expression_cluster (85)
Interaction (20)
Map_infoMapIVPosition-26.7831Error0.004516
PositivePositive_cloneR02D3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00032281
WBPaper00038491
WBPaper00055090
WBPaper00061547
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene