Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00019624

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00019624SMapS_parentSequenceK10C9
IdentityVersion3
NameCGC_namernst-2Person_evidenceWBPerson26011
Sequence_nameK10C9.3
Molecular_nameK10C9.3
K10C9.3.1
CE28601
Other_nameCELE_K10C9.3Accession_evidenceNDBBX284605
Public_namernst-2
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:01WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
224 Oct 2018 11:13:03WBPerson1983Name_changeCGC_namernst-2
312 Nov 2018 16:28:50WBPerson1983Name_changeCGC_namernst-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrnst
Allele (184)
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (34)
Structured_descriptionAutomated_descriptionPredicted to enable RNA endonuclease activity. Predicted to be involved in RNA catabolic process. Predicted to be located in extracellular region. Expressed in several structures, including intestine; neuronal sheath cell; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in several diseases, including RNASET2-deficient cystic leukoencephalopathy; adenocarcinoma (multiple); and mismatch repair cancer syndrome. Is an ortholog of human RNASET2 (ribonuclease T2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3883Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
DOID:234Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
DOID:0081007Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
DOID:0050861Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
DOID:3717Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
DOID:1324Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
DOID:1909Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
DOID:5410Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
DOID:0112182Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21686)
Molecular_infoCorresponding_CDSK10C9.3
Corresponding_transcriptK10C9.3.1
Other_sequence (17)
Associated_featureWBsf999247
WBsf1019127
WBsf231377
Experimental_infoRNAi_resultWBRNAi00000936Inferred_automaticallyRNAi_primary
WBRNAi00050508Inferred_automaticallyRNAi_primary
WBRNAi00016966Inferred_automaticallyRNAi_primary
WBRNAi00034248Inferred_automaticallyRNAi_primary
Expr_patternExpr13850
Expr1012890
Expr1038474
Expr1154219
Expr2005022
Expr2023241
Drives_constructWBCnstr00025720
WBCnstr00040096
Construct_productWBCnstr00025720
WBCnstr00040096
Microarray_results (24)
Expression_clusterWBPaper00030922:glycosylated_protein
WBPaper00032031:DConiospora_downregulated_cDNA_12h
WBPaper00032031:DConiospora_downregulated_cDNA_24h
WBPaper00032425:down_in_zfp-1
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:bodywall-muscle_larva_enriched
WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:pharyngeal-muscle_embryo_enriched
WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
WBPaper00044260:nicotic-acid_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(gk119)_upregulated
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045257:bar-1(ga80)_downregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_upregulated
WBPaper00045809:rsd-2(yp10)_downregulated
WBPaper00047132:glp-1(ts)-25C_upregulated
WBPaper00048988:daf-2(e1370)_daf-16(mu86)_downregulated_neuron
WBPaper00048988:neuron_expressed
WBPaper00049098:heat-induced_hrde-1(tm1200)
WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
WBPaper00050053:muscle_enriched_Day4
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00051404:alg-1(gk214)_downregulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053814:15C_downregulated_OP50
WBPaper00053814:15C_downregulated_PY79
WBPaper00054410:set-26(tm2467)_downregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056161:hermaphrodite_enriched_siRNA
WBPaper00056443:DietaryRestriction_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056826:SGP_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057006:DietaryRestriction_downregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
WBPaper00057162:meg-3_meg-4_downregulated_sRNA
WBPaper00057288:Cold_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00059224:tph-1(mg280)_upregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060445:nfki-1(cer1)_downregulated_L4
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060661:sensory-neuron_depleted
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:ABarpaaa_lineage
WBPaper00061340:ADA_ADE_grandparent
WBPaper00061340:AIN_parent
WBPaper00061340:AVH_parent
WBPaper00061340:Body_wall_muscle
WBPaper00061340:Ciliated_amphid_neuron
WBPaper00061340:Intestine
WBPaper00061340:RID_parent
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
WBPaper00061527:K10C9.3_8160-Y39G8B.1_58
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062590:Aging_upregulated_neuron
WBPaper00062669:extracellular-vesicle_protein
WBPaper00063930:BRD-1_interacting
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064716:paraquat_downregulated
WBPaper00064871:hypoxia_downregulated_F1
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_upregulated_cisplatin
WBPaper00065841:4_0
WBPaper00065841:4_1
WBPaper00065841:4_2
WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
WBPaper00066085:sin-3(tm1276)_upregulated
cgc4386_cluster_6_2
cgc4386_cluster_6_4
cgc4489_group_10
cgc4489_group_20
WBPaper00025032:cluster_2
WBPaper00025141:N2_Expressed_Genes
WBPaper00029437:dcr-1_upregulated
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032062:age_regulated_genes
WBPaper00032165:differentially_expressed_with_age_medoid_1
WBPaper00034739:N2lessDR1350
WBPaper00036286:Pattern_D
WBPaper00036383:ash-2_L3_regulated
WBPaper00037695:CC_3-day
WBPaper00038172:tax-6null_down_regulated
WBPaper00039866:ClassComp_daf-19_upregulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040876:mir-35_upregulated
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00040963:TA200_down
WBPaper00040963:TA300_down
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041960:N2_fasting_upregulated_9hto12h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
[cgc5376]:let-60(G12V)-regulated_genes
[cgc5767]:cluster_2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_ET
[cgc5767]:expression_class_ET_max(122_min)
[cgc5767]:expression_class_E_pi(23_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
[cgc5767]:expression_class_MET
[cgc6390]:Cluster_C
[cgc6390]:Cluster_D
[cgc6390]:mixed_spermatogenesis-somatic
InteractionWBInteraction000149860
WBInteraction000241298
WBInteraction000546251
WBInteraction000549405
WBInteraction000568276
WBInteraction000579531
Map_infoMapVPosition-19.8553
PositivePositive_cloneK10C9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055004
WBPaper00055090
WBPaper00058870
WBPaper00059755
WBPaper00063730
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene