WormBase Tree Display for Gene: WBGene00019066

WBGene00019066 SMap: S_parent: Sequence: F58G4
  Identity: Version: 2
    Name: CGC_name: sdz-23 Paper_evidence: WBPaper00024645
          Person_evidence: WBPerson374
      Sequence_name: F58G4.4
      Molecular_name: F58G4.4
        F58G4.4.1
        CE07309
      Other_name: CELE_F58G4.4 Accession_evidence: NDB BX284605
      Public_name: sdz-23
    DB_info: Database: AceView gene 5I575
        WormQTL gene WBGene00019066
        WormFlux gene WBGene00019066
        NDB locus_tag CELE_F58G4.4
        NCBI gene 186544
        RefSeq protein NM_072690.2
        TREEFAM TREEFAM_ID TF318345
        TrEMBL UniProtAcc Q20997
        UniProt_GCRP UniProtAcc Q20997
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 19 Aug 2005 17:08:06 WBPerson2970 Name_change: CGC_name: sdz-23
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sdz
    Allele (19)
    Strain: WBStrain00035073
    RNASeq_FPKM (74)
    GO_annotation: 00069891
      00069892
    Ortholog (15)
    Structured_description: Concise_description: sdz-23 encodes a putatively secreted protein with a single EGF domain, with some similarity to LAG-2; sdz-23 begins to be expressed in the E blastomere of 8-cell embryos, and continues to be expressed solely in the E lineage througout embryogenesis; sdz-23 requires SKN-1 and WRM-1 for E lineage expression, and is a putative MED-1/2 target gene; sdz-23 is both activated by POP-1 (with SYS-1 as coactivator, in the E lineage) and repressed by POP-1 (in the MS lineage), while the dependence of sdz-23 on WRM-1 for E lineage expression is alleviated by loss of POP-1, indicating that WRM-1 switches POP-1 from repression to activation in the E lineage; sdz-23 requires SYS-1 for normal embryonic expression; SDZ-23 has no obvious function in mass RNAi assays. Paper_evidence: WBPaper00024645
            WBPaper00024981
            WBPaper00026704
            WBPaper00031416
          Person_evidence: WBPerson396
          Curator_confirmed: WBPerson567
          Date_last_updated: 18 Jan 2008 00:00:00
      Automated_description: Predicted to enable Notch binding activity. Predicted to be located in membrane. Expressed in E; Ea; and Ep. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F58G4.4
    Corresponding_transcript: F58G4.4.1
  Experimental_info: RNAi_result: WBRNAi00067715 Inferred_automatically: RNAi_primary
      WBRNAi00033132 Inferred_automatically: RNAi_primary
      WBRNAi00049052 Inferred_automatically: RNAi_primary
      WBRNAi00016014 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3142
      Expr3500
      Expr3643
      Expr1023512
      Expr1038233
      Expr1152793
      Expr2015681
      Expr2033914
    Drives_construct: WBCnstr00004704
      WBCnstr00011170
      WBCnstr00011433
      WBCnstr00026087
    Construct_product: WBCnstr00021775
      WBCnstr00021916
      WBCnstr00026087
    Microarray_results (18)
    Expression_cluster (47)
    Interaction (100)
  Map_info: Map: V Position: 1.01024 Error: 0.000371
    Positive: Positive_clone: F58G4 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5433
        4560
    Pseudo_map_position
  Reference: WBPaper00026581
    WBPaper00038341
    WBPaper00045713
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene