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WormBase Tree Display for Gene: WBGene00018451

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Name Class

WBGene00018451SMapS_parentSequenceF45D11
IdentityVersion2
NameSequence_nameF45D11.4
Molecular_nameF45D11.4
Other_nameCELE_F45D11.4Accession_evidenceNDBBX284602
Public_nameF45D11.4
DB_infoDatabaseAceViewgene2B297
WormQTLgeneWBGene00018451
NDBlocus_tagCELE_F45D11.4
NCBIgene185782
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:00WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
224 May 2006 09:58:03WBPerson1867EventChanged_classCDSPseudogene
StatusLive
Gene_infoBiotypeSO:0000336
Allele (23)
RNASeq_FPKM (74)
ParalogWBGene00018459Caenorhabditis elegansFrom_analysismodENCODE_Pseudogenes
Structured_descriptionConcise_descriptionF45D11.4, with F45D11.2 and F45D11.3, encodes a nematode-specific protein that entirely consists of one large (~300-residue) 'domain of unknown function' (DUF684) that is found in several other C. elegans proteins; a transcription unit of either F45D11.4, F45D11.2, or F45D11.3 (genes of essentially identical sequence) has a natural nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that at least one of these three genes is a natural substrate for SMG-mediated nonsense suppresssion; since several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-8, rpl-10a, rpl-12) have protein products that are involved in translation, F45D11.4 protein may may function in translation as well.Paper_evidenceWBPaper00004313
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including sesamin; Rifampin; and allantoin based on microarray and RNA-seq studies.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDS_historyF45D11.4:wp159
Corresponding_pseudogeneF45D11.4
Experimental_infoMicroarray_resultsSMD_F45D11.N
SMD_F45D11.O
SMD_F45D11.P
SMD_F45D11.Q
172593_x_at
185601_s_at
GPL19516_CGZ0021811
GPL21109_F45D11.3
Expression_cluster (63)
InteractionWBInteraction000502142
Map_infoPositivePositive_cloneF45D11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII-15.5737
RemarkIt appears that curators meant to convert this into a Pseudogene in 2005 but this never happened and so was finally done in 2006.
MethodGene