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WormBase Tree Display for Gene: WBGene00018426

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Name Class

WBGene00018426SMapS_parentSequenceF44E7
IdentityVersion1
NameSequence_nameF44E7.4
Molecular_name (12)
Other_nameCELE_F44E7.4Accession_evidenceNDBBX284605
Public_nameF44E7.4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:00WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (64)
RNASeq_FPKM (74)
GO_annotation00027573
00027574
00027575
00027576
00027577
00027578
00027579
00027580
00027581
00123575
Contained_in_operonCEOP5565
Ortholog (40)
Paralog (11)
Structured_descriptionAutomated_descriptionPredicted to enable metalloendopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis involved in protein catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in gonad. Human ortholog(s) of this gene implicated in Alzheimer's disease; diabetic encephalopathy; and type 2 diabetes mellitus. Is an ortholog of human IDE (insulin degrading enzyme).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5381)
DOID:0050850Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5381)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5381)
Molecular_infoCorresponding_CDSF44E7.4a
F44E7.4b
F44E7.4c
F44E7.4d
Corresponding_transcriptF44E7.4a.1
F44E7.4b.1
F44E7.4c.1
F44E7.4d.1
Other_sequence (23)
Associated_featureWBsf652650
WBsf652651
WBsf1000085
WBsf233722
WBsf233723
Experimental_infoRNAi_resultWBRNAi00014943Inferred_automaticallyRNAi_primary
WBRNAi00014942Inferred_automaticallyRNAi_primary
WBRNAi00047301Inferred_automaticallyRNAi_primary
Expr_patternExpr4017
Expr1022310
Expr1037941
Expr1151157
Expr2003723
Expr2021942
Drives_constructWBCnstr00026526
Construct_productWBCnstr00026526
Microarray_results (36)
Expression_cluster (140)
Interaction (175)
Map_infoPositivePositive_cloneF44E7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV-0.99921
ReferenceWBPaper00038491
WBPaper00055090
MethodGene