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WormBase Tree Display for Gene: WBGene00018227

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Name Class

WBGene00018227SMapS_parentSequenceF40B5
IdentityVersion2
NameCGC_namenep-15Person_evidenceWBPerson260
Sequence_nameF40B5.3
Molecular_nameF40B5.3a
F40B5.3a.1
CE47906
F40B5.3b
CE49781
F40B5.3b.1
F40B5.3b.2
F40B5.3c
Other_nameCELE_F40B5.3Accession_evidenceNDBBX284606
Public_namenep-15
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:00WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
210 Feb 2012 15:49:10WBPerson2970Name_changeCGC_namenep-15
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnep
Allele (51)
StrainWBStrain00037285
RNASeq_FPKM (74)
GO_annotation00123412
00123413
00123414
Ortholog (92)
Paralog (24)
Structured_descriptionConcise_descriptionF40B5.3 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F40B5.3 has no clear orthologs in other organisms.Paper_evidenceWBPaper00004584
WBPaper00013276
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF40B5.3a
F40B5.3b
Corresponding_CDS_historyF40B5.3:wp227
F40B5.3a:wp234
F40B5.3b:wp243
Corresponding_transcriptF40B5.3c
F40B5.3a.1
F40B5.3b.1
F40B5.3b.2
Experimental_infoRNAi_resultWBRNAi00046818Inferred_automaticallyRNAi_primary
Expr_patternExpr1016107
Expr1150692
Expr2013960
Expr2032199
Drives_constructWBCnstr00026684
Construct_productWBCnstr00026684
Microarray_results (17)
Expression_cluster (76)
SAGE_tagSAGE:tgtgacaaggaacgagaStrandSense
Unambiguously_mapped
Map_infoMapXPosition-0.15367
PositivePositive_cloneF40B5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene