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WormBase Tree Display for Gene: WBGene00017971

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Name Class

WBGene00017971SMapS_parentSequenceF32A5
IdentityVersion1
NameSequence_nameF32A5.8
Molecular_nameF32A5.8
F32A5.8.1
CE32642
F32A5.8.2
Other_nameCELE_F32A5.8Accession_evidenceNDBBX284602
Public_nameF32A5.8
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:59WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (28)
RNASeq_FPKM (74)
GO_annotation00088416
Ortholog (49)
Paralog (11)
Structured_descriptionAutomated_descriptionEnriched in several structures, including ABplppppaa; XXX cell; interfacial epithelial cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; short chain dehydrogenase; and NAD(P)-binding domain superfamily. Is an ortholog of human WWOX (WW domain containing oxidoreductase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3748Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:5041Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:0080452Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:0080060Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:1749Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
Molecular_infoCorresponding_CDSF32A5.8
Corresponding_CDS_historyF32A5.8:wp88
Corresponding_transcriptF32A5.8.1
F32A5.8.2
Other_sequenceDviv_isotig26603
FK809915.1
ES741830.1
HBC06410_1
JI168537.1
EX911002.1
CRC02292_1
BXC02105_1
EX010470.1
Experimental_infoRNAi_resultWBRNAi00046080Inferred_automaticallyRNAi_primary
Expr_patternExpr1027266
Expr1037732
Expr1149970
Expr2003199
Expr2021411
Drives_constructWBCnstr00026875
Construct_productWBCnstr00026875
Microarray_results (16)
Expression_cluster (149)
InteractionWBInteraction000285108
WBInteraction000442245
WBInteraction000576420
WBInteraction000578762
Map_infoPositivePositive_cloneF32A5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII0.500032
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00062625
MethodGene