WormBase Tree Display for Gene: WBGene00017842
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| WBGene00017842 | SMap | S_parent | Sequence | F26G1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | nep-12 | Person_evidence | WBPerson260 | |||||
| Sequence_name | F26G1.6 | ||||||||
| Molecular_name | F26G1.6a | ||||||||
| F26G1.6a.1 | |||||||||
| CE53804 | |||||||||
| F26G1.6b | |||||||||
| CE53937 | |||||||||
| F26G1.6b.1 | |||||||||
| Other_name | CELE_F26G1.6 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | nep-12 | ||||||||
| DB_info | Database | AceView | gene | 2F66 | |||||
| WormQTL | gene | WBGene00017842 | |||||||
| WormFlux | gene | WBGene00017842 | |||||||
| NDB | locus_tag | CELE_F26G1.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00017842|UniProtKB=Q19831 | |||||||
| family | PTHR11733 | ||||||||
| NCBI | gene | 173824 | |||||||
| RefSeq | protein | NM_001377790.1 | |||||||
| NM_001377789.2 | |||||||||
| TrEMBL | UniProtAcc | A0A5S9MNU9 | |||||||
| A0A5S9MND8 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A5S9MNU9 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 10 Feb 2012 15:49:10 | WBPerson2970 | Name_change | CGC_name | nep-12 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nep | ||||||||
| Allele (139) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (46) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | F26G1.6 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while F26G1.6 has no clear orthologs in other organisms, it falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes). | Paper_evidence | WBPaper00004584 | |||||
| WBPaper00013276 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Is an ortholog of human KEL (Kell metallo-endopeptidase (Kell blood group)). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F26G1.6a | |||||||
| F26G1.6b | |||||||||
| Corresponding_CDS_history | F26G1.6:wp107 | ||||||||
| F26G1.6:wp130 | |||||||||
| F26G1.6:wp274 | |||||||||
| Corresponding_transcript | F26G1.6a.1 | ||||||||
| F26G1.6b.1 | |||||||||
| Other_sequence (11) | |||||||||
| Associated_feature | WBsf650014 | ||||||||
| WBsf650015 | |||||||||
| WBsf665476 | |||||||||
| WBsf665477 | |||||||||
| WBsf717656 | |||||||||
| WBsf717657 | |||||||||
| WBsf987696 | |||||||||
| WBsf987697 | |||||||||
| WBsf1012126 | |||||||||
| WBsf1012127 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00089060 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00031469 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013975 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045688 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1011602 | ||||||||
| Expr1037671 | |||||||||
| Expr1149601 | |||||||||
| Expr2013958 | |||||||||
| Expr2032197 | |||||||||
| Drives_construct | WBCnstr00026969 | ||||||||
| Construct_product | WBCnstr00026969 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (136) | |||||||||
| Interaction | WBInteraction000139204 | ||||||||
| WBInteraction000416466 | |||||||||
| WBInteraction000559851 | |||||||||
| WBInteraction000578348 | |||||||||
| Map_info | Map | II | Position | -3.0646 | |||||
| Positive | Positive_clone | F26G1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00011735 | ||||||||
| WBPaper00019195 | |||||||||
| WBPaper00064648 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
