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WormBase Tree Display for Gene: WBGene00017770

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Name Class

WBGene00017770SMapS_parentSequenceF25B4
IdentityVersion1
NameSequence_nameF25B4.7
Molecular_nameF25B4.7
F25B4.7.1
CE35287
Other_nameCELE_F25B4.7Accession_evidenceNDBBX284605
Public_nameF25B4.7
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:59WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (24)
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (50)
Paralog (35)
Structured_descriptionAutomated_descriptionPredicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
DOID:0110429Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
DOID:0080335Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
DOID:699Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
DOID:11984Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
DOID:11727Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
DOID:0111517Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
DOID:12558Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
DOID:0080130Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10990)
Molecular_infoCorresponding_CDSF25B4.7
Corresponding_CDS_historyF25B4.7:wp106
Corresponding_transcriptF25B4.7.1
Other_sequence (15)
Associated_featureWBsf652646
WBsf668652
WBsf981937
WBsf233715
Experimental_infoRNAi_resultWBRNAi00013849Inferred_automaticallyRNAi_primary
WBRNAi00045470Inferred_automaticallyRNAi_primary
Expr_patternExpr1011362
Expr1037634
Expr1149389
Expr2002945
Expr2021161
Drives_constructWBCnstr00027033
Construct_productWBCnstr00027033
Microarray_results (26)
Expression_cluster (99)
Interaction (14)
Map_infoPositivePositive_cloneF25B4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV-1.24052
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00062301
MethodGene