WormBase Tree Display for Gene: WBGene00017687
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| WBGene00017687 | SMap | S_parent | Sequence | F22A3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | ets-4 | Person_evidence | WBPerson1997 | |||||
| WBPerson3209 | |||||||||
| Sequence_name | F22A3.1 | ||||||||
| Molecular_name | F22A3.1a | ||||||||
| F22A3.1a.1 | |||||||||
| CE34001 | |||||||||
| F22A3.1b | |||||||||
| CE28824 | |||||||||
| F22A3.1b.1 | |||||||||
| Other_name | CELE_F22A3.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | ets-4 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00017687 | |||||
| WormFlux | gene | WBGene00017687 | |||||||
| NDB | locus_tag | CELE_F22A3.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00017687|UniProtKB=A8WFJ9 | |||||||
| family | PTHR11849 | ||||||||
| NCBI | gene | 180927 | |||||||
| RefSeq | protein | NM_076698.6 | |||||||
| NM_001373331.1 | |||||||||
| SwissProt | UniProtAcc | A8WFJ9 | |||||||
| UniProt_GCRP | UniProtAcc | A8WFJ9 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 18 Jul 2005 13:34:00 | WBPerson2970 | Name_change | CGC_name | ets-4 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ets | ||||||||
| Allele (58) | |||||||||
| Strain | WBStrain00001431 | ||||||||
| WBStrain00031382 | |||||||||
| WBStrain00008267 | |||||||||
| WBStrain00008269 | |||||||||
| WBStrain00008270 | |||||||||
| WBStrain00008271 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (33) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Automated_description | Enables DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of axon extension involved in regeneration and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including P1; germ line; head; socket cell; and sperm. Human ortholog(s) of this gene implicated in ovarian cancer. Is an ortholog of human SPDEF (SAM pointed domain containing ETS transcription factor). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:2394 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17257) | ||||
| Molecular_info | Corresponding_CDS | F22A3.1a | |||||||
| F22A3.1b | |||||||||
| Corresponding_CDS_history | F22A3.1:wp99 | ||||||||
| F22A3.1:wp184 | |||||||||
| F22A3.1b:wp271 | |||||||||
| Corresponding_transcript | F22A3.1a.1 | ||||||||
| F22A3.1b.1 | |||||||||
| Other_sequence (13) | |||||||||
| Associated_feature (16) | |||||||||
| Transcription_factor | WBTranscriptionFactor000389 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00001910 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00013719 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045262 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00002313 | ||||||||
| WBCnstr00010822 | |||||||||
| WBCnstr00012660 | |||||||||
| WBCnstr00013737 | |||||||||
| WBCnstr00016643 | |||||||||
| WBCnstr00019904 | |||||||||
| WBCnstr00027101 | |||||||||
| Construct_product | WBCnstr00013737 | ||||||||
| WBCnstr00016644 | |||||||||
| WBCnstr00016645 | |||||||||
| WBCnstr00027101 | |||||||||
| Regulate_expr_cluster | WBPaper00037624:ets-4(ok165)_downregulated | ||||||||
| WBPaper00037624:ets-4(ok165)_upregulated | |||||||||
| WBPaper00064473:ets-4(rrr16)_downregulated | |||||||||
| WBPaper00064473:ets-4(rrr16)_upregulated | |||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (207) | |||||||||
| Interaction (50) | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| Map_info | Map | X | Position | -2.85101 | Error | 0.011627 | |||
| Positive | Positive_clone | F22A3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5358 | |||||||
| 5261 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (26) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
