WormBase Tree Display for Gene: WBGene00017437
expand all nodes | collapse all nodes | view schema
| WBGene00017437 | SMap | S_parent | Sequence | F13H8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | nmgp-1 | Person_evidence | WBPerson1847 | |||||
| Sequence_name | F13H8.4 | ||||||||
| Molecular_name | F13H8.4 | ||||||||
| F13H8.4.1 | |||||||||
| CE35476 | |||||||||
| Other_name | CELE_F13H8.4 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | nmgp-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 20 Dec 2007 11:31:35 | WBPerson2970 | Name_change | CGC_name | nmgp-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nmgp | ||||||||
| Allele (23) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00064731 | ||||||||
| 00064732 | |||||||||
| 00064733 | |||||||||
| 00122825 | |||||||||
| Contained_in_operon | CEOP2761 | ||||||||
| Ortholog (44) | |||||||||
| Structured_description | Concise_description | F13H8.4 encodes a homolog of the human neuronal membrane glycoproteins PLP1 (OMIM:300401, mutated in Pelizaeus-Merzbacher disease and spastic paraplegia), M6A (OMIM:601275), and M6B (OMIM:300051); the presence of a myelin-related protein in C. elegans is currently unexplained, but suggests that some evolutionary precursor of myelin may exist in invertebrates, perhaps involving septate junctions between cells. | Paper_evidence | WBPaper00028828 | |||||
| WBPaper00028839 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 11 Dec 2006 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in neuron projection development. Predicted to be located in plasma membrane. Expressed in several structures, including cephalic sheath cell; neurons; somatic nervous system; tail ganglion; and ventral ganglion. Used to study depressive disorder. Human ortholog(s) of this gene implicated in Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Is an ortholog of human GPM6A (glycoprotein M6A); GPM6B (glycoprotein M6B); and PLP1 (proteolipid protein 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:1596 | Homo sapiens | Paper_evidence | WBPaper00062210 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 20 Jul 2022 00:00:00 | ||||||||
| Potential_model | DOID:0110773 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9086) | |||||
| DOID:3210 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9086) | ||||||
| Models_disease_asserted | WBDOannot00001289 | ||||||||
| Molecular_info | Corresponding_CDS | F13H8.4 | |||||||
| Corresponding_CDS_history | F13H8.4:wp107 | ||||||||
| Corresponding_transcript | F13H8.4.1 | ||||||||
| Other_sequence (20) | |||||||||
| Associated_feature | WBsf644264 | ||||||||
| WBsf981207 | |||||||||
| WBsf988116 | |||||||||
| WBsf1012354 | |||||||||
| WBsf221413 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00116236 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00044560 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116239 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116241 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116237 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116242 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116238 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030915 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116240 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr16049 | ||||||||
| Expr1023498 | |||||||||
| Expr1037501 | |||||||||
| Expr1148517 | |||||||||
| Expr2014331 | |||||||||
| Expr2032572 | |||||||||
| Drives_construct | WBCnstr00027301 | ||||||||
| WBCnstr00042737 | |||||||||
| Construct_product | WBCnstr00027301 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (172) | |||||||||
| Interaction | WBInteraction000269487 | ||||||||
| WBInteraction000312085 | |||||||||
| WBInteraction000379908 | |||||||||
| WBInteraction000388919 | |||||||||
| WBInteraction000455587 | |||||||||
| Map_info | Map | II | Position | -0.392446 | Error | 0.000747 | |||
| Positive | Positive_clone | F13H8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062210 | |||||||||
| WBPaper00063593 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
