farl-11 is an ortholog of human STRIP2 (striatin interacting protein 2) and STRIP1 (striatin interacting protein 1); FARL-11 is required for normal ER dynamics and the membrane localization of GLP-1 in the germline; translation of farl-11 mRNA in the mitotic germline is promoted by PUF-8; FARL-11::GFP expressed under the endogenous promoter and 3' UTR localizes to endoplasmic reticulum and the nuclear membrane in the germline and embryos.
Involved in endoplasmic reticulum organization; epithelial tube morphogenesis; and positive regulation of endocytic recycling. Located in endoplasmic reticulum. Expressed in germ line. Is an ortholog of human STRIP1 (striatin interacting protein 1) and STRIP2 (striatin interacting protein 2).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.