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WormBase Tree Display for Gene: WBGene00017131

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Name Class

WBGene00017131SMapS_parentSequenceE04F6
IdentityVersion1
NameSequence_nameE04F6.15
Molecular_nameE04F6.15
E04F6.15.1
CE27908
Other_nameCELE_E04F6.15Accession_evidenceNDBBX284602
Public_nameE04F6.15
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (26)
RNASeq_FPKM (74)
GO_annotation00088544
Ortholog (34)
Paralog (11)
Structured_descriptionAutomated_descriptionEnriched in intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; short chain dehydrogenase; and NAD(P)-binding domain superfamily. Is an ortholog of human WWOX (WW domain containing oxidoreductase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3748Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:5041Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:0080452Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:0080060Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:1749Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
Molecular_infoCorresponding_CDSE04F6.15
Corresponding_transcriptE04F6.15.1
Other_sequenceName_isotig03722
CSC00044_1
EX563461.1
FD517749.1
Acan_isotig16988
Associated_featureWBsf223311
Experimental_infoRNAi_resultWBRNAi00043679Inferred_automaticallyRNAi_primary
WBRNAi00043680Inferred_automaticallyRNAi_primary
Expr_patternExpr1012120
Expr1147664
Expr2020379
Drives_constructWBCnstr00027546
Construct_productWBCnstr00027546
Microarray_results (16)
Expression_cluster (163)
InteractionWBInteraction000047022
WBInteraction000047030
WBInteraction000047031
Map_infoPositivePositive_cloneE04F6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII0.499478
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00065331
MethodGene