WormBase Tree Display for Gene: WBGene00017082
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| WBGene00017082 | SMap | S_parent | Sequence | DC2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | Sequence_name | DC2.5 | |||||||
| Molecular_name | DC2.5a | ||||||||
| DC2.5a.1 | |||||||||
| CE42420 | |||||||||
| DC2.5b | |||||||||
| Other_name | CELE_DC2.5 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | DC2.5 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele (48) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00100722 | ||||||||
| Ortholog (33) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Automated_description | Enriched in several structures, including ABplpppapa; ABprpppapa; anal sphincter muscle; rectal epithelial cell; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including TPEN; Alovudine; and stavudine based on RNA-seq; proteomic; and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; short chain dehydrogenase; and NAD(P)-binding domain superfamily. Is an ortholog of human WWOX (WW domain containing oxidoreductase). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3748 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||
| DOID:5041 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||||
| DOID:0080452 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||||
| DOID:0080060 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||||
| DOID:1749 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||||
| Molecular_info | Corresponding_CDS | DC2.5a | |||||||
| Corresponding_CDS_history | DC2.5:wp88 | ||||||||
| DC2.5:wp125 | |||||||||
| DC2.5:wp188 | |||||||||
| Corresponding_transcript | DC2.5b | ||||||||
| DC2.5a.1 | |||||||||
| Other_sequence | Oden_isotig21742 | ||||||||
| Associated_feature | WBsf652436 | ||||||||
| WBsf668708 | |||||||||
| WBsf999097 | |||||||||
| WBsf999098 | |||||||||
| WBsf999099 | |||||||||
| WBsf1019030 | |||||||||
| WBsf1019031 | |||||||||
| WBsf233243 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00043540 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00012615 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1025881 | ||||||||
| Expr1037341 | |||||||||
| Expr1147532 | |||||||||
| Expr2002107 | |||||||||
| Expr2020332 | |||||||||
| Microarray_results (15) | |||||||||
| Expression_cluster (212) | |||||||||
| Interaction | WBInteraction000471081 | ||||||||
| WBInteraction000585656 | |||||||||
| Map_info | Positive | Positive_clone | DC2 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | V | -20.0099 | |||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
