WormBase Tree Display for Gene: WBGene00016971

WBGene00016971 SMap: S_parent: Sequence: C56E6
  Identity: Version: 2
    Name: CGC_name: toe-2 Person_evidence: WBPerson3232
            WBPerson555
      Sequence_name: C56E6.3
      Molecular_name: C56E6.3a
        C56E6.3a.1
        CE04275
        C56E6.3b
        CE35261
        C56E6.3a.2
        C56E6.3b.1
        C56E6.3b.2
      Other_name: CELE_C56E6.3 Accession_evidence: NDB BX284602
      Public_name: toe-2
    DB_info: Database: AceView gene 2G808
        WormQTL gene WBGene00016971
        WormFlux gene WBGene00016971
        NDB locus_tag CELE_C56E6.3
        Panther gene CAEEL|WormBase=WBGene00016971|UniProtKB=H2KZH5
          family PTHR16206
        NCBI gene 174076
        RefSeq protein NM_001383867.2
            NM_001026872.4
        SwissProt UniProtAcc H2KZH5
        UniProt_GCRP UniProtAcc H2KZH5
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 02 Mar 2009 11:15:07 WBPerson9133 Name_change: CGC_name: toe-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: toe
    Allele (50)
    Strain: WBStrain00032804
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (29)
    Paralog: WBGene00002368 Caenorhabditis elegans From_analysis: Panther
      WBGene00011427 Caenorhabditis elegans From_analysis: Panther
      WBGene00015342 Caenorhabditis elegans From_analysis: Panther
      WBGene00016052 Caenorhabditis elegans From_analysis: Panther
      WBGene00077693 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Automated_description: Predicted to enable kinase activity. Involved in positive regulation of apoptotic process and regulation of asymmetric cell division. Predicted to be located in several cellular components, including centrosome; chromosome; and midbody. Expressed in several structures, including QL.aa; QL.pp; QR.aa; QR.pp; and oxygen sensory neurons. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C56E6.3a
      C56E6.3b
    Corresponding_transcript: C56E6.3a.1
      C56E6.3a.2
      C56E6.3b.1
      C56E6.3b.2
    Other_sequence: CRC06143_1
      CJC15075_1
      CBC00603_1
      CR00772
      CRC04680_1
      CJC00306_1
      CBC13452_1
      CR06309
    Associated_feature: WBsf650153
      WBsf665619
      WBsf223192
      WBsf223193
  Experimental_info: RNAi_result: WBRNAi00043278 Inferred_automatically: RNAi_primary
      WBRNAi00085111 Inferred_automatically: RNAi_primary
      WBRNAi00022310 Inferred_automatically: RNAi_primary
      WBRNAi00030205 Inferred_automatically: RNAi_primary
      WBRNAi00062175 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11869
      Expr11870
      Expr1028889
      Expr1037284
      Expr1147256
      Expr2017442
      Expr2035581
    Drives_construct: WBCnstr00019692
      WBCnstr00027667
      WBCnstr00040175
      WBCnstr00040176
    Construct_product: WBCnstr00019407
      WBCnstr00027667
    Microarray_results (24)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00040209:B.thuringiensis_upregulated_N2
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045486:starvation_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00048988:daf-16(mu86)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049942:HeatShock_downregulated_hsf-1(+)
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:GABAergic-neuron_enriched
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00051461:pig-1(gm344)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055897:heat-shock_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:AVH_parent
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:Ciliated_non_amphid_neuron
      WBPaper00061340:I2_grandparent
      WBPaper00061340:M4_parent
      WBPaper00061340:Neuroblast_AFD_RMD
      WBPaper00061340:Neuroblast_AIZ_FLP
      WBPaper00061340:Neuroblast_AIZ_FLP_RMG
      WBPaper00061340:Neuroblast_ASE_ASJ_AUA
      WBPaper00061340:Neuroblast_HSN_PHB
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061340:Parent_of_AMsh_URB
      WBPaper00061340:Parent_of_exc_duct_pore_DB_1_3
      WBPaper00061340:Parent_of_hyp1V_and_ant_arc_V
      WBPaper00061340:Parent_of_tail_spike_and_hyp10
      WBPaper00061340:PLM_ALN_great_grandparent
      WBPaper00061340:RIA_parent
      WBPaper00061340:RID_parent
      WBPaper00061340:URA_parent
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:F54E7.8-orc-5_6376
      WBPaper00061651:Spermatheca_enriched
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062056:lin-36(we36)_upregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065841:43_0
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00025032:cluster_58
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030985:Enterococcus_faecalis_upregulated
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00038060:SUMO-1_upregulated
      WBPaper00040426:CYD-1_CDK-4_upregulated
      WBPaper00040426:CYE-1_CDK-2AF_upregulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040963:TA300_down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
    Interaction (128)
  Map_info: Map: II Position: -0.197136 Error: 0.003119
    Positive: Positive_clone: C56E6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00032961
    WBPaper00045422
    WBPaper00048732
    WBPaper00062068
    WBPaper00064561
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene