Involved in innate immune response. Predicted to be located in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human ANGPT2 (angiopoietin 2) and ANGPT4 (angiopoietin 4).