WormBase Tree Display for Gene: WBGene00016768

WBGene00016768 SMap: S_parent: Sequence: C49C8
  Identity: Version: 2
    Name: CGC_name: cyp-33E1
      Sequence_name: C49C8.4
      Molecular_name: C49C8.4
        C49C8.4.1
        CE31452
        C49C8.4.2
      Other_name: CELE_C49C8.4 Accession_evidence: NDB BX284604
      Public_name: cyp-33E1
    DB_info: Database: AceView gene 4J410
        WormQTL gene WBGene00016768
        WormFlux gene WBGene00016768
        NDB locus_tag CELE_C49C8.4
        Panther gene CAEEL|WormBase=WBGene00016768|UniProtKB=Q27482
          family PTHR24300
        NCBI gene 183602
        RefSeq protein NM_069079.6
        TrEMBL UniProtAcc Q27482
        UniProt_GCRP UniProtAcc Q27482
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 21 Sep 2004 09:38:16 WBPerson1971 Name_change: CGC_name: cyp-33E1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cyp
    Allele (51)
    Strain: WBStrain00031731
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (75)
    Paralog (44)
    Structured_description: Automated_description: Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including end stage renal disease; human immunodeficiency virus infectious disease; and renal hypertension. Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C8 (cytochrome P450 family 2 subfamily C member 8); and CYP2F1 (cytochrome P450 family 2 subfamily F member 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9974 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2615)
      DOID:783 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2622)
      DOID:1073 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2622)
      DOID:9828 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2615)
      DOID:9976 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2615)
      DOID:399 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2615)
      DOID:0050742 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2615)
      DOID:526 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2615)
      DOID:9119 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2615)
  Molecular_info: Corresponding_CDS: C49C8.4
    Corresponding_CDS_history: C49C8.4:wp82
    Corresponding_transcript: C49C8.4.1
      C49C8.4.2
    Other_sequence (14)
    Associated_feature: WBsf652007
      WBsf1017868
      WBsf230446
  Experimental_info: RNAi_result: WBRNAi00012135 Inferred_automatically: RNAi_primary
      WBRNAi00029976 Inferred_automatically: RNAi_primary
      WBRNAi00090636 Inferred_automatically: RNAi_primary
      WBRNAi00012134 Inferred_automatically: RNAi_primary
      WBRNAi00092668 Inferred_automatically: RNAi_primary
      WBRNAi00042792 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8191
      Expr1028716
      Expr1146775
      Expr2010723
      Expr2028961
    Drives_construct: WBCnstr00004997
      WBCnstr00027817
    Construct_product: WBCnstr00027817
    Antibody: WBAntibody00002185
      WBAntibody00002224
    Microarray_results (17)
    Expression_cluster (121)
    Interaction (40)
  Map_info: Map: IV Position: 3.92656 Error: 0.001619
    Positive: Positive_clone: C49C8 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4874
    Pseudo_map_position
  Reference: WBPaper00031529
    WBPaper00031939
    WBPaper00036179
    WBPaper00038491
    WBPaper00042257
    WBPaper00055090
    WBPaper00065331
    WBPaper00065988
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene