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WormBase Tree Display for Gene: WBGene00016608

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Name Class

WBGene00016608SMapS_parentSequenceC43E11
IdentityVersion2
NameCGC_namecogc-5Person_evidenceWBPerson9844
Sequence_nameC43E11.11
Molecular_nameC43E11.11
C43E11.11.1
CE32607
Other_nameCELE_C43E11.11Accession_evidenceNDBBX284601
Public_namecogc-5
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
205 Aug 2009 09:22:32WBPerson9133Name_changeCGC_namecogc-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcogc
Allele (54)
StrainWBStrain00032539
RNASeq_FPKM (74)
GO_annotation00050119
00050120
00122191
00122192
Contained_in_operonCEOP1164
Ortholog (29)
Structured_descriptionConcise_descriptioncogc-5 encodes an ortholog of mammalian COG-5, a subunit of lobe B of the conserved oligomeric Golgi complex (COGC); COGC-5 is also orthologous to Drosophila FOUR WAY STOP (required for fly spermatogenesis); COGC-5 is weakly required for normal gonadal distal tip cell migration, a process that also requires seven other orthologs of COGC subunits; like other lobe B subunits in both C. elegans and S. cerevisiae, COGC-5 is only partially required for normal function, while lobe A subunits are strongly required in either worms or yeast.Paper_evidenceWBPaper00026979
WBPaper00028363
WBPaper00028599
WBPaper00028601
WBPaper00028603
Curator_confirmedWBPerson567
Date_last_updated30 Jul 2009 00:00:00
Automated_descriptionPredicted to be involved in intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be part of Golgi transport complex. Expressed in gonad. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIi. Is an ortholog of human COG5 (component of oligomeric golgi complex 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070261Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:14857)
Molecular_infoCorresponding_CDSC43E11.11
Corresponding_CDS_historyC43E11.11:wp90
Corresponding_transcriptC43E11.11.1
Other_sequence (17)
Associated_featureWBsf656182
WBsf217508
Experimental_infoRNAi_resultWBRNAi00064303Inferred_automaticallyRNAi_primary
WBRNAi00099107Inferred_automaticallyRNAi_primary
WBRNAi00003139Inferred_automaticallyRNAi_primary
WBRNAi00042380Inferred_automaticallyRNAi_primary
WBRNAi00117054Inferred_automaticallyRNAi_primary
WBRNAi00113518Inferred_automaticallyRNAi_primary
WBRNAi00001792Inferred_automaticallyRNAi_primary
Expr_patternExpr4010
Expr1023075
Expr1037132
Expr1146368
Expr2010294
Expr2028536
Drives_constructWBCnstr00027940
WBCnstr00027941
Construct_productWBCnstr00027940
WBCnstr00027941
Microarray_results (23)
Expression_cluster (93)
Interaction (34)
Map_infoMapIPosition-1.53789Error0.002724
PositivePositive_cloneC43E11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00064339
Remarkcogc-5 was originally assigned in error to C43E11.1.Paper_evidenceWBPaper00026979
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene