Predicted to enable mannose-1-phosphate guanylyltransferase (GTP) activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2T; congenital muscular dystrophy-dystroglycanopathy A14; and muscular dystrophy-dystroglycanopathy type B14. Is an ortholog of human GMPPB (GDP-mannose pyrophosphorylase B).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.