WormBase Tree Display for Gene: WBGene00016162

WBGene00016162 SMap: S_parent: Sequence: C27D6
  Identity: Version: 2
    Name: CGC_name: crh-2 Person_evidence: WBPerson625
            WBPerson567
            WBPerson2812
      Sequence_name: C27D6.4
      Molecular_name (12)
      Other_name: CELE_C27D6.4 Accession_evidence: NDB BX284602
      Public_name: crh-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 26 Apr 2011 16:30:24 WBPerson2970 Name_change: CGC_name: crh-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: crh
    Allele (122)
    Strain: WBStrain00002482
      WBStrain00003552
      WBStrain00037697
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog: WBGene00025415 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            Inparanoid_8
            WormBase-Compara
      WBGene00057413 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00142654 Caenorhabditis brenneri From_analysis: Inparanoid_8
      WBGene00135506 Caenorhabditis japonica From_analysis: Inparanoid_8
      CSP28.g14662 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP31.g16977 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g4409 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g15955 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      FL83_06014 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_005972 Caenorhabditis remanei From_analysis: WormBase-Compara
      Sp34_20097200 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g4441 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00246886 Onchocerca volvulus From_analysis: WormBase-Compara
      FB:FBgn0004396 Drosophila melanogaster From_analysis: Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-030219-181 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-070112-1542 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      HGNC:2347 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      HGNC:23720 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      HGNC:18855 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      HGNC:18856 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      HGNC:18854 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      MGI:99946 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            SonicParanoid
      MGI:1347062 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      MGI:1916603 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      MGI:2442695 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      MGI:2384786 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      RGD:1308831 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            PhylomeDB
            SonicParanoid
      RGD:1359278 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      RGD:1308152 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      RGD:1359613 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      RGD:1306040 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
    Paralog: WBGene00000222 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000793 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002783 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in defense response to Gram-negative bacterium; positive regulation of dauer entry; and regulation of gene expression. Predicted to be located in nucleus. Expressed in body wall musculature; seam cell; spermatheca; and tail. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16; prostate adenocarcinoma; and prostate carcinoma in situ. Is an ortholog of human CREB3L1 (cAMP responsive element binding protein 3 like 1) and CREB3L2 (cAMP responsive element binding protein 3 like 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110345 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18856)
      DOID:8634 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18854)
      DOID:2526 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18854)
  Molecular_info: Corresponding_CDS: C27D6.4a
      C27D6.4b
      C27D6.4c
      C27D6.4d
    Corresponding_CDS_history: C27D6.4a:wp88
      C27D6.4b:wp88
      C27D6.4c:wp88
      C27D6.4c:wp238
    Corresponding_transcript: C27D6.4a.1
      C27D6.4b.1
      C27D6.4c.1
      C27D6.4d.1
    Other_sequence (13)
    Associated_feature (22)
    Gene_product_binds (376)
    Transcription_factor: WBTranscriptionFactor000319
  Experimental_info: RNAi_result: WBRNAi00011256 Inferred_automatically: RNAi_primary
      WBRNAi00011620 Inferred_automatically: RNAi_primary
      WBRNAi00092881 Inferred_automatically: RNAi_primary
      WBRNAi00041346 Inferred_automatically: RNAi_primary
      WBRNAi00011257 Inferred_automatically: RNAi_primary
      WBRNAi00041345 Inferred_automatically: RNAi_primary
      WBRNAi00092155 Inferred_automatically: RNAi_primary
      WBRNAi00090568 Inferred_automatically: RNAi_primary
    Expr_pattern (13)
    Drives_construct: WBCnstr00003072
      WBCnstr00004526
      WBCnstr00004531
      WBCnstr00028283
    Construct_product: WBCnstr00016813
      WBCnstr00017350
      WBCnstr00028283
    Microarray_results (43)
    Expression_cluster (97)
    Interaction (35)
  Map_info: Map: II Position: -1.94895 Error: 0.002445
    Positive: Positive_clone: C27D6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027076
    WBPaper00031111
    WBPaper00038491
    WBPaper00041549
    WBPaper00055090
    WBPaper00058109
    WBPaper00059852
    WBPaper00060467
    WBPaper00061738
    WBPaper00064315
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene