WormBase Tree Display for Gene: WBGene00015248
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| WBGene00015248 | SMap | S_parent | Sequence | B0546 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mai-2 | Person_evidence | WBPerson71 | |||||
| Sequence_name | B0546.1 | ||||||||
| Molecular_name | B0546.1 | ||||||||
| B0546.1.1 | |||||||||
| CE16792 | |||||||||
| Other_name | 4E151 | Accession_evidence | EMBL | AF326939 | |||||
| CELE_B0546.1 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | mai-2 | ||||||||
| DB_info | Database | AceView | gene | 4E151 | |||||
| WormQTL | gene | WBGene00015248 | |||||||
| WormFlux | gene | WBGene00015248 | |||||||
| NDB | locus_tag | CELE_B0546.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00015248|UniProtKB=O44441 | |||||||
| family | PTHR23407 | ||||||||
| NCBI | gene | 177106 | |||||||
| RefSeq | protein | NM_067935.9 | |||||||
| SwissProt | UniProtAcc | O44441 | |||||||
| TREEFAM | TREEFAM_ID | TF320659 | |||||||
| UniProt_GCRP | UniProtAcc | O44441 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 13 Oct 2006 11:22:39 | WBPerson2970 | Name_change | CGC_name | mai-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mai | ||||||||
| Allele (20) | |||||||||
| Possibly_affected_by | WBVar02158609 | ||||||||
| WBVar02158610 | |||||||||
| Strain | WBStrain00002870 | ||||||||
| WBStrain00052821 | |||||||||
| WBStrain00052822 | |||||||||
| WBStrain00052826 | |||||||||
| WBStrain00052827 | |||||||||
| WBStrain00052828 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00003124 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00013708 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mai-2/B0546.1 is orthologous to mitochondrial intrinsic ATPase inhibitorprotein (IF(1)), which blocks reverse action (ATP hydrolysis) byF(0)F(1)-ATPase when its (normally required) proton gradient is lost;MAI-2 has a mitochondrial import signal at its N-terminus, and istransported to yeast mitochondria; MAI-2 can inhibit yeastF(0)F(1)-ATPase, and this inhibition is pH-dependent; MAI-2's tertiarystructure is dominated by beta-strands and random loops. | Paper_evidence | WBPaper00028361 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 12 Oct 2006 00:00:00 | ||||||||
| Automated_description | Enables ATPase inhibitor activity. Predicted to be involved in heme biosynthetic process. Located in mitochondrion. Expressed in germ line and tail. Is an ortholog of human ATP5IF1 (ATP synthase inhibitory factor subunit 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | B0546.1 | |||||||
| Corresponding_transcript | B0546.1.1 | ||||||||
| Other_sequence (84) | |||||||||
| Associated_feature | WBsf645870 | ||||||||
| WBsf645871 | |||||||||
| WBsf981718 | |||||||||
| WBsf995950 | |||||||||
| WBsf995951 | |||||||||
| WBsf1017070 | |||||||||
| WBsf1017071 | |||||||||
| WBsf228096 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00039181 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00033357 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00009847 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1709 | ||||||||
| Expr5085 | |||||||||
| Expr13497 | |||||||||
| Expr1015246 | |||||||||
| Expr1036531 | |||||||||
| Expr1143326 | |||||||||
| Expr2013357 | |||||||||
| Expr2031589 | |||||||||
| Drives_construct | WBCnstr00003390 | ||||||||
| WBCnstr00039554 | |||||||||
| WBCnstr00042804 | |||||||||
| WBCnstr00042805 | |||||||||
| Construct_product | WBCnstr00039554 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (152) | |||||||||
| Interaction (22) | |||||||||
| Map_info | Map | IV | Position | -4.55224 | Error | 0.010154 | |||
| Positive | Positive_clone | B0546 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028361 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00043855 | |||||||||
| WBPaper00052941 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061615 | |||||||||
| WBPaper00062370 | |||||||||
| WBPaper00064661 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
