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WormBase Tree Display for Gene: WBGene00015235

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Name Class

WBGene00015235SMapS_parentSequenceB0511
IdentityVersion4
NameCGC_namecdc-26Person_evidenceWBPerson8
WBPerson205
Sequence_nameB0511.9
Molecular_name (12)
Other_namemat-4Person_evidenceWBPerson8
WBPerson205
tag-265
CELE_B0511.9Accession_evidenceNDBBX284601
Public_namecdc-26
DB_infoDatabaseAceViewgene1L216
WormQTLgeneWBGene00015235
WormFluxgeneWBGene00015235
NDBlocus_tagCELE_B0511.9
NCBIgene172958
RefSeqproteinNM_171844.7
NM_001264516.3
NM_001264518.2
NM_170919.7
SwissProtUniProtAccG4RT11
TREEFAMTREEFAM_IDTF319639
UniProt_GCRPUniProtAccG4RT11
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:55WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
208 Sep 2006 10:43:24WBPerson1847Name_changeCGC_namemat-4
316 Feb 2007 14:30:49WBPerson2970Name_changeCGC_namecdc-26
Other_namemat-4
406 Mar 2007 10:44:50WBPerson2970EventAcquires_mergeWBGene00044320
Name_changeOther_nametag-265
Acquires_mergeWBGene00044320
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcdc
Allele (22)
StrainWBStrain00036119
RNASeq_FPKM (74)
GO_annotation00009130
00009131
00009132
00009133
00009134
00009135
Contained_in_operonCEOP1632
Ortholog (16)
Structured_descriptionConcise_descriptioncdc-26 encodes, by alternative splicing, two isoforms of a probableanaphase-promoting complex/cyclosome (APC/C) component that has crypticorthology to budding yeast Cdc26p, and that is required for normalmeiosis and asymmetric one-cell embryonic division; although CDC-26 andCdc26p have little obvious sequence similarity, they do share a commonmotif in their N-terminal domains, and yeast cdc26 mutants can berescued by transgenic C. elegans CDC-26; CDC-26 binds EMB-27 in yeasttwo-hybrid experiments; weak cdc-26(RNAi) induces loss of asymmetryduring the first embryonic cell division of AB/P1, while strongcdc-26(RNAi) arrests embryos at meiotic metaphase I; in weakly defectiveone-cell cdc-26(RNAi) embryos, PAR-3 is mislocalized from the anteriorto the entire cortex, while PAR-2 is mislocalized from the posteriorcortex to cytoplasm.Paper_evidenceWBPaper00006332
WBPaper00029199
Curator_confirmedWBPerson567
Date_last_updated08 May 2007 00:00:00
Automated_descriptionPredicted to be involved in cell division; meiotic cell cycle; and protein ubiquitination. Predicted to be located in nucleus. Expressed in germ line.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSB0511.9a
B0511.9b
B0511.9c
B0511.9d
Corresponding_CDS_historyB0511.9a:wp185
B0511.9a:wp214
B0511.9b:wp185
Corresponding_transcriptB0511.9a.1
B0511.9b.1
B0511.9c.1
B0511.9d.1
Other_sequenceCBC13072_1
CR01858
CRC01910_1
Associated_featureWBsf220266
Experimental_infoRNAi_result (13)
Expr_patternExpr4084
Expr1012460
Expr1036525
Expr1143307
Expr2009783
Expr2028023
Drives_constructWBCnstr00028983
Construct_productWBCnstr00028983
Microarray_results (32)
Expression_cluster (120)
Interaction (26)
Map_infoMapIPosition5.05944Error9.9e-05
PositivePositive_cloneB0511Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00024733
WBPaper00029199
WBPaper00041771
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene