WormBase Tree Display for Gene: WBGene00012722

WBGene00012722 SMap: S_parent: Sequence: Y39G8B
  Identity: Version: 1
    Name: Sequence_name: Y39G8B.1
      Molecular_name: Y39G8B.1a
        Y39G8B.1a.1
        CE21733
        Y39G8B.1b
        CE24243
        Y39G8B.1a.2
        Y39G8B.1b.1
      Other_name: CELE_Y39G8B.1 Accession_evidence: NDB BX284602
      Public_name: Y39G8B.1
    DB_info: Database: AceView gene 2O262
        WormQTL gene WBGene00012722
        WormFlux gene WBGene00012722
        NDB locus_tag CELE_Y39G8B.1
        Panther gene CAEEL|WormBase=WBGene00012722|UniProtKB=Q9NAI5
          family PTHR11732
        NCBI gene 175047
        RefSeq protein NM_001383987.1
            NM_064523.3
        TrEMBL UniProtAcc Q9U2J6
            Q9NAI5
        UniProt_GCRP UniProtAcc Q9NAI5
        OMIM gene 600450
            600451
            604741
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (136)
    Strain: WBStrain00036408
    RNASeq_FPKM (74)
    GO_annotation: 00096123
      00096124
      00119755
    Contained_in_operon: CEOP2723
    Ortholog: WBGene00039667 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00057634 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00158170 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00149422 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00122561 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00121011 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00137197 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00226745 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g12688 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g5085 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g11613 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g1334 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g13648 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g9492 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g1884 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g10937 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g7376 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g27193 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g3270 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g5549 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_01163.g15861 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-Y39G8B.1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g19482 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00101.g4294 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_03418.g30126 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_03986.g31778 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_06895 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_005759 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g09278 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g13452 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20067600 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g6455 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00247381 Onchocerca volvulus From_analysis: WormBase-Compara
      SGD:S000002776 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            SonicParanoid
      SGD:S000005646 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            SonicParanoid
      FB:FBgn0033101 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            SonicParanoid
      FB:FBgn0035476 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            SonicParanoid
      FB:FBgn0027552 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            SonicParanoid
      FB:FBgn0086254 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      FB:FBgn0036183 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            Panther
            SonicParanoid
      FB:FBgn0036290 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-040625-7 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-040808-44 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-041210-132 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-050417-118 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:381 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:387 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
            SonicParanoid
      HGNC:384 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
            SonicParanoid
      HGNC:385 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
            SonicParanoid
      HGNC:388 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
            SonicParanoid
      HGNC:386 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
            SonicParanoid
      HGNC:380 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:382 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:23437 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            Panther
            SonicParanoid
      HGNC:37281 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1353494 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      MGI:101918 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      MGI:107673 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1351662 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1914758 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Panther
      MGI:1929955 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:1915111 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1918111 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1933427 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1351661 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:2092 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      RGD:68346 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:620257 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            Panther
      RGD:708475 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoInspector
            Panther
      RGD:1311841 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      RGD:1308277 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoInspector
            Panther
      RGD:1309599 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            Panther
      RGD:1306847 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1562954 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1359406 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1559604 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
            PhylomeDB
    Paralog (13)
    Structured_description: Automated_description: Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including acute lymphoblastic leukemia (multiple); artery disease (multiple); and carcinoma (multiple). Is an ortholog of human AKR1B1 (aldo-keto reductase family 1 member B); AKR1B10 (aldo-keto reductase family 1 member B10); and AKR1B15 (aldo-keto reductase family 1 member B15). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (19)
  Molecular_info: Corresponding_CDS: Y39G8B.1a
      Y39G8B.1b
    Corresponding_transcript: Y39G8B.1a.1
      Y39G8B.1a.2
      Y39G8B.1b.1
    Other_sequence (66)
    Associated_feature: WBsf666350
      WBsf224227
      WBsf224228
  Experimental_info: RNAi_result: WBRNAi00092613 Inferred_automatically: RNAi_primary
      WBRNAi00056283 Inferred_automatically: RNAi_primary
      WBRNAi00036955 Inferred_automatically: RNAi_primary
      WBRNAi00002078 Inferred_automatically: RNAi_primary
      WBRNAi00020416 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1010776
      Expr1035631
      Expr1159766
      Expr2007400
      Expr2025635
    Microarray_results (29)
    Expression_cluster (166)
    Interaction (156)
  Map_info: Positive: Positive_clone: Y39G8B Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II 21.6711
  Reference: WBPaper00038491
    WBPaper00041022
    WBPaper00042257
    WBPaper00046585
    WBPaper00055090
  Method: Gene