WormBase Tree Display for Gene: WBGene00012031
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| WBGene00012031 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | gpdh-3 | Person_evidence | ||||||
| Sequence_name | T25G3.4 | ||||||||
| Molecular_name | T25G3.4 | ||||||||
| T25G3.4.1 | |||||||||
| CE14180 | |||||||||
| Other_name | CELE_T25G3.4 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | gpdh-3 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 04 Jul 2019 11:28:17 | WBPerson1983 | Name_change | CGC_name | gpdh-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gpdh | ||||||||
| Allele (49) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Contained_in_operon | CEOP1400 | ||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00013049 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | T25G3.4 encodes a putative mitochondrial glycerol-3-phosphatedehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2(OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcriptsare not obviously enriched during oogenesis, but T25G3.4 is predicted tobe coexpressed in an operon with chs-1 and T25G3.3; such coexpression,if real, may simply reflect all three genes being required foroogenesis, rather than some more detailed functional connection; T25G3.4has no obvious function in mass RNAi assays. | Paper_evidence | WBPaper00026721 | |||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Apr 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable calcium ion binding activity and sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity. Predicted to be involved in glycerol catabolic process and glycerol-3-phosphate metabolic process. Predicted to be located in mitochondrion. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human GPD2 (glycerol-3-phosphate dehydrogenase 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4456) | ||||
| Molecular_info | Corresponding_CDS | T25G3.4 | |||||||
| Corresponding_transcript | T25G3.4.1 | ||||||||
| Other_sequence (68) | |||||||||
| Associated_feature | WBsf656541 | ||||||||
| WBsf218028 | |||||||||
| WBsf218029 | |||||||||
| WBsf218030 | |||||||||
| WBsf218031 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00116985 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00004306 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00110146 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00054162 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035977 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00084392 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076710 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1028584 | ||||||||
| Expr1035320 | |||||||||
| Expr1157708 | |||||||||
| Expr2006516 | |||||||||
| Expr2024735 | |||||||||
| Drives_construct | WBCnstr00030185 | ||||||||
| Construct_product | WBCnstr00030185 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (124) | |||||||||
| Interaction (46) | |||||||||
| Map_info | Map | I | Position | 2.14985 | |||||
| Positive | Positive_clone | T25G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00042257 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
