WormBase Tree Display for Gene: WBGene00011398
expand all nodes | collapse all nodes | view schema
WBGene00011398 | SMap | S_parent | Sequence | T03F6 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | qdpr-1 | Person_evidence | WBPerson384 | |||||
Sequence_name | T03F6.1 | ||||||||
Molecular_name | T03F6.1 | ||||||||
T03F6.1.1 | |||||||||
CE16335 | |||||||||
Other_name | CELE_T03F6.1 | Accession_evidence | NDB | BX284603 | |||||
Public_name | qdpr-1 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 28 Sep 2005 14:42:19 | WBPerson2970 | Name_change | CGC_name | qdpr-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | qdpr | ||||||||
Allele (21) | |||||||||
Strain (2) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00102545 | ||||||||
00102546 | |||||||||
00102547 | |||||||||
00102548 | |||||||||
00102549 | |||||||||
00102550 | |||||||||
00102551 | |||||||||
00102552 | |||||||||
Ortholog (43) | |||||||||
Structured_description | Concise_description | The T03F6.1 gene encodes an ortholog of the human gene QUINOID DIHYDROPTERIDINE REDUCTASE (QDPR; DHPR), which when mutated leads to phenylketonuria II (OMIM:261630). | Paper_evidence | WBPaper00004637 | |||||
Curator_confirmed | WBPerson1823 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable 6,7-dihydropteridine reductase activity; NADH binding activity; and NADPH binding activity. Predicted to be involved in L-phenylalanine catabolic process and tetrahydrobiopterin biosynthetic process. Predicted to be located in cytoplasm. Expressed in several structures, including CEP; gonad; hypodermis; serotonergic neurons; and tail. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia C and phenylketonuria. Is an ortholog of human QDPR (quinoid dihydropteridine reductase). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0081130 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9752) | ||||
DOID:9281 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9752) | ||||||
Molecular_info | Corresponding_CDS | T03F6.1 | |||||||
Corresponding_transcript | T03F6.1.1 | ||||||||
Other_sequence (56) | |||||||||
Associated_feature | WBsf645709 | ||||||||
WBsf994875 | |||||||||
WBsf1016363 | |||||||||
WBsf226000 | |||||||||
WBsf226001 | |||||||||
Experimental_info | RNAi_result | WBRNAi00006277 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00052289 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00006916 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00035099 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00018078 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00044398 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr11444 | ||||||||
Expr12168 | |||||||||
Expr13109 | |||||||||
Expr1015613 | |||||||||
Expr1035014 | |||||||||
Expr1155920 | |||||||||
Expr2015209 | |||||||||
Expr2033443 | |||||||||
Drives_construct | WBCnstr00020339 | ||||||||
WBCnstr00020340 | |||||||||
WBCnstr00020347 | |||||||||
WBCnstr00030688 | |||||||||
Construct_product | WBCnstr00020340 | ||||||||
WBCnstr00030688 | |||||||||
Microarray_results (20) | |||||||||
Expression_cluster (156) | |||||||||
Interaction | WBInteraction000119924 | ||||||||
WBInteraction000119983 | |||||||||
WBInteraction000123091 | |||||||||
WBInteraction000155681 | |||||||||
WBInteraction000163454 | |||||||||
WBInteraction000193449 | |||||||||
WBInteraction000217580 | |||||||||
WBInteraction000220987 | |||||||||
WBInteraction000224071 | |||||||||
WBInteraction000226361 | |||||||||
WBInteraction000236772 | |||||||||
WBInteraction000239318 | |||||||||
WBInteraction000244814 | |||||||||
WBInteraction000247737 | |||||||||
WBInteraction000248091 | |||||||||
WBInteraction000248835 | |||||||||
WBInteraction000258900 | |||||||||
WBInteraction000284154 | |||||||||
WBInteraction000290711 | |||||||||
WBInteraction000295422 | |||||||||
WBInteraction000295475 | |||||||||
WBInteraction000297135 | |||||||||
WBInteraction000300755 | |||||||||
WBInteraction000301034 | |||||||||
WBInteraction000331130 | |||||||||
WBInteraction000333561 | |||||||||
WBInteraction000353880 | |||||||||
WBInteraction000358114 | |||||||||
WBInteraction000370435 | |||||||||
WBInteraction000379059 | |||||||||
WBInteraction000386083 | |||||||||
WBInteraction000386957 | |||||||||
WBInteraction000387712 | |||||||||
WBInteraction000396740 | |||||||||
WBInteraction000402726 | |||||||||
WBInteraction000405816 | |||||||||
WBInteraction000410651 | |||||||||
WBInteraction000415177 | |||||||||
WBInteraction000415898 | |||||||||
WBInteraction000419051 | |||||||||
WBInteraction000421962 | |||||||||
WBInteraction000424021 | |||||||||
WBInteraction000426842 | |||||||||
WBInteraction000446095 | |||||||||
WBInteraction000452918 | |||||||||
WBInteraction000456451 | |||||||||
WBInteraction000458915 | |||||||||
WBInteraction000521513 | |||||||||
WBInteraction000548326 | |||||||||
WBInteraction000548619 | |||||||||
WBInteraction000551683 | |||||||||
WBInteraction000577936 | |||||||||
WBInteraction000580756 | |||||||||
Map_info | Map | III | Position | 21.213 | Error | 4.5e-05 | |||
Positive | Positive_clone | T03F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00034518 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00046585 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |