WormBase Tree Display for Gene: WBGene00011181

WBGene00011181 SMap: S_parent: Sequence: R09H10
  Identity: Version: 1
    Name: Sequence_name: R09H10.3
      Molecular_name: R09H10.3a
        R09H10.3a.1
        CE34083
        R09H10.3b
        CE12662
        R09H10.3b.1
      Other_name: CELE_R09H10.3 Accession_evidence: NDB BX284604
      Public_name: R09H10.3
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (22)
    RNASeq_FPKM (74)
    GO_annotation: 00073201
      00073202
      00073203
      00073204
      00073205
      00073206
      00073207
      00073208
      00118464
      00118465
    Ortholog: WBGene00027104 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00142124 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00131424 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00076953 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g8785 Caenorhabditis bovis From_analysis: WormBase-Compara
      CBOVI.g8829 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g1467 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g21663 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7350 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g6509 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g12244 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g19121 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g15691 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g6705 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00669.g13305 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_IV.g14998 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g17732 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00322.g9389 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_14071 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014939 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g09017 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g17013 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40090800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11633 Caenorhabditis elegans From_analysis: WormBase-Compara
      FB:FBgn0050016 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040927-14 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-161215-1 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-060825-253 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:12405 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:98865 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1916142 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:3916 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1309350 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog: WBGene00022808 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: R09H10.3 is orthologous to the human gene TRANSTHYRETIN (PREALBUMIN, AMYLOIDOSIS TYPE I) (TTR; OMIM:176300), which when mutated leads to disease. Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 06 Aug 2004 00:00:00
      Automated_description: Enables identical protein binding activity. Predicted to be involved in purine nucleobase metabolic process. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carpal tunnel syndrome 1; colorectal adenoma; and gastrointestinal system cancer (multiple). Is an ortholog of human TTR (transthyretin). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (13)
  Molecular_info: Corresponding_CDS: R09H10.3a
      R09H10.3b
    Corresponding_CDS_history: R09H10.3:wp101
    Corresponding_transcript: R09H10.3a.1
      R09H10.3b.1
    Other_sequence (19)
    Associated_feature: WBsf646315
      WBsf646316
      WBsf013952
      WBsf229008
  Experimental_info: RNAi_result: WBRNAi00022857 Inferred_automatically: RNAi_primary
      WBRNAi00034793 Inferred_automatically: RNAi_primary
      WBRNAi00051648 Inferred_automatically: RNAi_primary
      WBRNAi00017668 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1010795
      Expr1155319
      Expr2005525
      Expr2023744
    Drives_construct: WBCnstr00000541
      WBCnstr00030868
    Construct_product: WBCnstr00030868
    Microarray_results (25)
    Expression_cluster (206)
    Interaction (21)
  Map_info: Positive: Positive_clone: R09H10 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: IV 4.64132
  Reference: WBPaper00032062
    WBPaper00038491
    WBPaper00055090
    WBPaper00065331
  Method: Gene