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WormBase Tree Display for Gene: WBGene00010924

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Name Class

WBGene00010924SMapS_parentSequenceM153
IdentityVersion2
NameCGC_namepycr-1Person_evidenceWBPerson25195
Sequence_nameM153.1
Molecular_nameM153.1
M153.1.1
CE52530
Other_nameCELE_M153.1Accession_evidenceNDBBX284606
Public_namepycr-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
201 Jun 2020 11:25:31WBPerson1983Name_changeCGC_namepycr-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpycr
Allele (31)
RNASeq_FPKM (74)
GO_annotation00072037
00072038
00072039
00072040
00072041
00118236
00118237
Ortholog (42)
ParalogWBGene00018904Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIB; autosomal recessive cutis laxa type IIIB; and hypomyelinating leukodystrophy 10. Is an ortholog of human PYCR1 (pyrroline-5-carboxylate reductase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070137Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9721)
DOID:0060788Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:30262)
DOID:0070138Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9721)
Molecular_infoCorresponding_CDSM153.1
Corresponding_CDS_historyM153.1:wp263
Corresponding_transcriptM153.1.1
Other_sequence (44)
Associated_featureWBsf648590
WBsf1007224
WBsf236456
Experimental_infoRNAi_resultWBRNAi00034458Inferred_automaticallyRNAi_primary
WBRNAi00050975Inferred_automaticallyRNAi_primary
WBRNAi00017217Inferred_automaticallyRNAi_primary
Expr_patternExpr1027528
Expr1034798
Expr1154677
Expr2005245
Expr2023463
Drives_constructWBCnstr00031050
Construct_productWBCnstr00031050
Microarray_results (18)
Expression_cluster (193)
Interaction (154)
Map_infoPositivePositive_cloneM153Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionX7.00714
ReferenceWBPaper00026952
WBPaper00038491
WBPaper00055090
MethodGene