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WormBase Tree Display for Gene: WBGene00010912

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Name Class

WBGene00010912SMapS_parentSequenceM106
IdentityVersion2
NameCGC_namegmps-1Person_evidenceWBPerson260
Sequence_nameM106.4
Molecular_name (11)
Other_nameCELE_M106.4Accession_evidenceNDBBX284602
Public_namegmps-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
228 Sep 2012 14:29:00WBPerson2970Name_changeCGC_namegmps-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgmps
Allele (83)
RNASeq_FPKM (74)
GO_annotation (17)
Contained_in_operonCEOP2716
Ortholog (38)
Structured_descriptionConcise_descriptionM106.4 is orthologous to human GUANINE MONOPHOSPHATE SYNTHETASE (GMPS; OMIM:600358), a partner gene of MLL in treatment-related acute myeloid leukemia with the karyotype t(3;11)(q25;q23).Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated06 Aug 2004 00:00:00
Automated_descriptionPredicted to enable GMP synthase activity. Predicted to be involved in GMP biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia. Is an ortholog of human GMPS (guanine monophosphate synthase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0081082Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4378)
Molecular_infoCorresponding_CDSM106.4a
M106.4b
M106.4c
Corresponding_CDS_historyM106.4a:wp229
M106.4b:wp229
Corresponding_transcriptM106.4a.1
M106.4a.2
M106.4b.1
M106.4b.2
M106.4c.1
Other_sequence (30)
Associated_feature (16)
Experimental_infoRNAi_resultWBRNAi00017198Inferred_automaticallyRNAi_primary
WBRNAi00001862Inferred_automaticallyRNAi_primary
WBRNAi00050940Inferred_automaticallyRNAi_primary
Expr_patternExpr1028820
Expr1034792
Expr1154640
Expr2012155
Expr2030391
Drives_constructWBCnstr00031058
Construct_productWBCnstr00031058
Microarray_results (31)
Expression_cluster (101)
Interaction (181)
Map_infoMapIIPosition3.13014
PositivePositive_cloneM106Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00033469
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene