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WormBase Tree Display for Gene: WBGene00010762

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Name Class

WBGene00010762SMapS_parentSequenceK10H10
IdentityVersion1
NameSequence_nameK10H10.6
Molecular_nameK10H10.6
K10H10.6.1
CE53999
Other_nameCELE_K10H10.6Accession_evidenceNDBBX284602
Public_nameK10H10.6
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (35)
RNASeq_FPKM (74)
GO_annotation00101494
Ortholog (23)
Paralog (11)
Structured_descriptionAutomated_descriptionEnriched in ASER and RID based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on RNA-seq; tiling array; and microarray studies. Is affected by eight chemicals including aldicarb; methylmercuric chloride; and Mercuric Chloride based on microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; short chain dehydrogenase; and NAD(P)-binding domain superfamily. Is an ortholog of human WWOX (WW domain containing oxidoreductase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3748Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:5041Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:0080452Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:0080060Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:1749Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
Molecular_infoCorresponding_CDSK10H10.6
Corresponding_CDS_historyK10H10.6:wp274
Corresponding_transcriptK10H10.6.1
Other_sequencePPC17767_1
Associated_featureWBsf644861
WBsf990728
Experimental_infoRNAi_resultWBRNAi00050570Inferred_automaticallyRNAi_primary
WBRNAi00114796Inferred_automaticallyRNAi_primary
WBRNAi00103453Inferred_automaticallyRNAi_primary
WBRNAi00017000Inferred_automaticallyRNAi_primary
WBRNAi00034275Inferred_automaticallyRNAi_primary
Expr_patternExpr1028287
Expr1154279
Expr2005050
Expr2023270
Drives_constructWBCnstr00031163
Construct_productWBCnstr00031163
Microarray_results (15)
Expression_cluster (56)
InteractionWBInteraction000047021
WBInteraction000047028
WBInteraction000047029
WBInteraction000316165
WBInteraction000360585
WBInteraction000504581
Map_infoPositivePositive_cloneK10H10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII23.0389
ReferenceWBPaper00029387
WBPaper00038491
WBPaper00055090
MethodGene