WormBase Tree Display for Gene: WBGene00010478
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| WBGene00010478 | SMap | S_parent | Sequence | K01G5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | dkc-1 | Person_evidence | WBPerson260 | |||||
| Sequence_name | K01G5.5 | ||||||||
| Molecular_name | K01G5.5 | ||||||||
| K01G5.5.1 | |||||||||
| CE16195 | |||||||||
| Other_name | CELE_K01G5.5 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | dkc-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 02 Mar 2022 23:57:00 | WBPerson51134 | Name_change | CGC_name | dkc-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dkc | ||||||||
| Allele (34) | |||||||||
| Strain | WBStrain00037243 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Contained_in_operon | CEOP3842 | ||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | The K01G5.5 gene encodes an ortholog of human DYSKERIN (DKC1; OMIM:300126), which when mutated leads to X-linked dyskeratosis congenita (OMIM:305000); the K01G5.5 protein is predicted to be mitochondrial with 68% accuracy. | Paper_evidence | WBPaper00004103 | |||||
| WBPaper00004424 | |||||||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable pseudouridine synthase activity. Predicted to be involved in box H/ACA RNA 3'-end processing and pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Human ortholog(s) of this gene implicated in X-linked dyskeratosis congenita and aplastic anemia. Is an ortholog of human DKC1 (dyskerin pseudouridine synthase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:2729 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2890) | ||||
| DOID:12449 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2890) | ||||||
| DOID:0070025 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2890) | ||||||
| Molecular_info | Corresponding_CDS | K01G5.5 | |||||||
| Corresponding_transcript | K01G5.5.1 | ||||||||
| Other_sequence (91) | |||||||||
| Associated_feature | WBsf047618 | ||||||||
| WBsf645579 | |||||||||
| WBsf659539 | |||||||||
| WBsf976018 | |||||||||
| WBsf976019 | |||||||||
| WBsf981573 | |||||||||
| WBsf994137 | |||||||||
| WBsf225757 | |||||||||
| WBsf225758 | |||||||||
| WBsf225759 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00016410 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00049635 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002578 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033832 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001600 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007830 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1027254 | ||||||||
| Expr1034573 | |||||||||
| Expr1153363 | |||||||||
| Expr2004655 | |||||||||
| Expr2022883 | |||||||||
| Drives_construct | WBCnstr00031390 | ||||||||
| Construct_product | WBCnstr00031390 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (163) | |||||||||
| Interaction (397) | |||||||||
| Map_info | Map | III | Position | 5.19412 | |||||
| Positive | Positive_clone | K01G5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026935 | ||||||||
| WBPaper00030479 | |||||||||
| WBPaper00031949 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00054284 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
