WormBase Tree Display for Gene: WBGene00010408
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| WBGene00010408 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mboa-2 | Person_evidence | WBPerson1105 | |||||
| Sequence_name | H19N07.4 | ||||||||
| Molecular_name | H19N07.4a | ||||||||
| H19N07.4a.1 | |||||||||
| CE50291 | |||||||||
| H19N07.4b | |||||||||
| CE45868 | |||||||||
| H19N07.4b.1 | |||||||||
| Other_name | CELE_H19N07.4 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | mboa-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 09 Sep 2008 12:24:31 | WBPerson2970 | Name_change | CGC_name | mboa-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mboa | ||||||||
| Allele (41) | |||||||||
| Strain | WBStrain00036453 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Contained_in_operon | CEOP5272 | ||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00007174 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mboa-2 encodes a sterol O-acyltransferase orthologous to Drosophila MIDWAY, and to human DGAT1 (OMIM:604900); MBOA-2 has acyl-CoA:diacylglycerol O-acyltransferase activity when expressed in yeast; MBOA-2 has no obvious function in mass RNAi assays. | Paper_evidence | WBPaper00004554 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00012795 | |||||||||
| WBPaper00027263 | |||||||||
| WBPaper00031342 | |||||||||
| WBPaper00032174 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 14 Oct 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in cardiomyopathy; congenital diarrhea 7 with exudative enteropathy; and obesity. Is an ortholog of human DGAT1 (diacylglycerol O-acyltransferase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060778 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2843) | ||||
| DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2843) | ||||||
| DOID:0050700 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2843) | ||||||
| Molecular_info | Corresponding_CDS | H19N07.4a | |||||||
| H19N07.4b | |||||||||
| Corresponding_CDS_history | H19N07.4a:wp245 | ||||||||
| Corresponding_transcript | H19N07.4a.1 | ||||||||
| H19N07.4b.1 | |||||||||
| Other_sequence (51) | |||||||||
| Associated_feature | WBsf653078 | ||||||||
| WBsf669358 | |||||||||
| WBsf1001274 | |||||||||
| WBsf1020405 | |||||||||
| WBsf234505 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00033510 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00049437 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076524 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016282 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1022337 | ||||||||
| Expr1034540 | |||||||||
| Expr1153164 | |||||||||
| Expr2013435 | |||||||||
| Expr2031669 | |||||||||
| Drives_construct | WBCnstr00031435 | ||||||||
| Construct_product | WBCnstr00031435 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (149) | |||||||||
| Interaction (30) | |||||||||
| Map_info | Map | V | Position | 2.9524 | |||||
| Positive | Positive_clone | H19N07 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00042257 | |||||||||
| WBPaper00043187 | |||||||||
| WBPaper00051641 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060484 | |||||||||
| WBPaper00062625 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [200225 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (2.95132) | |||||||||
| Method | Gene |
