WormBase Tree Display for Gene: WBGene00010328

WBGene00010328 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 2
    Name: CGC_name: clc-14 Person_evidence: WBPerson260
      Sequence_name: F59C6.11
      Molecular_name: F59C6.11a
        F59C6.11a.1
        CE27178
        F59C6.11b
        CE54604
        F59C6.11b.1
      Other_name: CELE_F59C6.11 Accession_evidence: NDB BX284601
      Public_name: clc-14
    DB_info: Database: AceView gene 1L109
        WormQTL gene WBGene00010328
        WormFlux gene WBGene00010328
        NDB locus_tag CELE_F59C6.11
        Panther gene CAEEL|WormBase=WBGene00010328|UniProtKB=G5EG00
          family PTHR21759
        NCBI gene 172935
        RefSeq protein NM_060355.4
        TrEMBL UniProtAcc G5EG00
        UniProt_GCRP UniProtAcc G5EG00
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 26 Jan 2024 23:28:21 WBPerson51134 Name_change: CGC_name: clc-14
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: clc
    Allele (20)
    Strain: WBStrain00037348
    RNASeq_FPKM (74)
    GO_annotation: 00019249
    Ortholog (18)
    Paralog: WBGene00010324 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00018792 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00044792 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: F59C6.11 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F59C6.11 is worm-specific, with obvious homologs only in C. elegans; F59C6.11 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. Paper_evidence: WBPaper00004961
            WBPaper00005654
            WBPaper00005946
            WBPaper00005975
            WBPaper00012856
            WBPaper00018356
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be located in membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F59C6.11a
      F59C6.11b
    Corresponding_transcript: F59C6.11a.1
      F59C6.11b.1
    Other_sequence: CRC07578_1
      CJC13527_1
      CBC00482_1
    Associated_feature: WBsf643690
      WBsf643691
      WBsf656868
      WBsf656869
      WBsf218441
  Experimental_info: RNAi_result: WBRNAi00049160 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1018870
      Expr1152903
      Expr2004467
      Expr2022690
    Drives_construct: WBCnstr00031499
    Construct_product: WBCnstr00031499
    Microarray_results (17)
    Expression_cluster (155)
  Map_info: Map: I Position: 5.05471
    Positive: Positive_clone: F59C6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene