WormBase Tree Display for Gene: WBGene00010305
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| WBGene00010305 | SMap | S_parent | Sequence | F59A2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | Sequence_name | F59A2.5 | |||||||
| Molecular_name | F59A2.5 | ||||||||
| F59A2.5.1 | |||||||||
| CE01023 | |||||||||
| Other_name | CELE_F59A2.5 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | F59A2.5 | ||||||||
| DB_info | Database | AceView | gene | 3E495 | |||||
| WormQTL | gene | WBGene00010305 | |||||||
| WormFlux | gene | WBGene00010305 | |||||||
| NDB | locus_tag | CELE_F59A2.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00010305|UniProtKB=Q21019 | |||||||
| family | PTHR31283 | ||||||||
| NCBI | gene | 175444 | |||||||
| RefSeq | protein | NM_065303.4 | |||||||
| TrEMBL | UniProtAcc | Q21019 | |||||||
| UniProt_GCRP | UniProtAcc | Q21019 | |||||||
| OMIM | gene | 300060 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele | WBVar01500082 | ||||||||
| WBVar01498832 | |||||||||
| WBVar01500142 | |||||||||
| WBVar01500143 | |||||||||
| WBVar00393972 | |||||||||
| WBVar00393973 | |||||||||
| WBVar00815592 | |||||||||
| WBVar00259028 | |||||||||
| WBVar01606973 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00070016 | ||||||||
| 00070017 | |||||||||
| Contained_in_operon | CEOP3112 | ||||||||
| Ortholog (31) | |||||||||
| Structured_description | Concise_description | F59A2.5 encodes a moderately small (123-residue) protein; F59A2.5 isorthologous to Brugia 14979.m04575, and more distantly similar tobudding yeast Pcc1p, to human CTAG1B (OMIM:300156, cancer antigen),CTAG2 (OMIM:300396, melanoma antigen), and LAGE3 (OMIM:300060), and tomany other uncharacterized proteins, ~80-200 residues long, in animals,fungi, and plants; F59A2.5 is required for fertility and embryonicdevelopment in mass RNAi assays and is bound by CKU-80 in two-hybridassays; F59A2.5 is transcriptionally activated by HLH-2 and HLH-8, buthas no known expression pattern; while F59A2.5 is putatively secretedand its human homologs are antigens, its yeast homolog Pcc1p is thoughtto be a transcription factor. | Paper_evidence | WBPaper00005039 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00024925 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00027104 | |||||||||
| WBPaper00029286 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 02 May 2007 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in tRNA threonylcarbamoyladenosine metabolic process. Predicted to be part of EKC/KEOPS complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 2. Is an ortholog of human LAGE3 (L antigen family member 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080244 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:26058) | ||||
| Molecular_info | Corresponding_CDS | F59A2.5 | |||||||
| Corresponding_transcript | F59A2.5.1 | ||||||||
| Other_sequence | CBC17030_1 | ||||||||
| CJC16429_1 | |||||||||
| Associated_feature | WBsf645024 | ||||||||
| WBsf645025 | |||||||||
| WBsf645026 | |||||||||
| WBsf658747 | |||||||||
| WBsf224609 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00033156 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00061484 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00067660 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00049097 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016048 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006784 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram635 | ||||||||
| Expr3904 | |||||||||
| Expr1025290 | |||||||||
| Expr1034496 | |||||||||
| Expr1152838 | |||||||||
| Expr2004434 | |||||||||
| Expr2022656 | |||||||||
| Drives_construct | WBCnstr00002760 | ||||||||
| WBCnstr00011737 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (100) | |||||||||
| Interaction (53) | |||||||||
| Map_info | Positive | Positive_clone | F59A2 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | III | -6.97262 | |||||||
| Reference | WBPaper00042178 | ||||||||
| Method | Gene |
