WormBase Tree Display for Gene: WBGene00010070
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| WBGene00010070 | SMap | S_parent | Sequence | F54F11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | nep-17 | Person_evidence | WBPerson260 | |||||
| Sequence_name | F54F11.2 | ||||||||
| Molecular_name | F54F11.2a | ||||||||
| F54F11.2a.1 | |||||||||
| CE11095 | |||||||||
| F54F11.2b | |||||||||
| CE43217 | |||||||||
| F54F11.2b.1 | |||||||||
| Other_name | CELE_F54F11.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | nep-17 | ||||||||
| DB_info | Database | AceView | gene | 2N805 | |||||
| WormQTL | gene | WBGene00010070 | |||||||
| WormFlux | gene | WBGene00010070 | |||||||
| NDB | locus_tag | CELE_F54F11.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00010070|UniProtKB=O45569 | |||||||
| family | PTHR11733 | ||||||||
| NCBI | gene | 174996 | |||||||
| RefSeq | protein | NM_001267466.3 | |||||||
| NM_001267467.3 | |||||||||
| TrEMBL | UniProtAcc | B6VQ96 | |||||||
| O45569 | |||||||||
| UniProt_GCRP | UniProtAcc | O45569 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 10 Feb 2012 15:49:10 | WBPerson2970 | Name_change | CGC_name | nep-17 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nep | ||||||||
| Allele (316) | |||||||||
| Strain | WBStrain00037459 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (52) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | nep-17 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; NEP-17 has no clear orthologs in other organisms. | Paper_evidence | WBPaper00004584 | |||||
| WBPaper00013276 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 27 Mar 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Located in membrane raft. Expressed in intestine. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F54F11.2a | |||||||
| F54F11.2b | |||||||||
| Corresponding_transcript | F54F11.2a.1 | ||||||||
| F54F11.2b.1 | |||||||||
| Other_sequence (258) | |||||||||
| Associated_feature | WBsf644805 | ||||||||
| WBsf990443 | |||||||||
| WBsf990444 | |||||||||
| WBsf990445 | |||||||||
| WBsf1013651 | |||||||||
| WBsf1013652 | |||||||||
| WBsf1013653 | |||||||||
| WBsf222370 | |||||||||
| WBsf222371 | |||||||||
| WBsf222372 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00089087 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00048358 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015644 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001758 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4354 | ||||||||
| Expr1020636 | |||||||||
| Expr1034395 | |||||||||
| Expr1152153 | |||||||||
| Expr2013962 | |||||||||
| Expr2032201 | |||||||||
| Drives_construct | WBCnstr00031691 | ||||||||
| Construct_product | WBCnstr00031691 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (268) | |||||||||
| Interaction (73) | |||||||||
| Map_info | Map | II | Position | 17.8006 | |||||
| Positive | Positive_clone | F54F11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028802 | ||||||||
| WBPaper00029046 | |||||||||
| WBPaper00037777 | |||||||||
| WBPaper00043670 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061547 | |||||||||
| WBPaper00064293 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
