WormBase Tree Display for Gene: WBGene00009865

WBGene00009865 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 1
    Name: Sequence_name: F49B2.6
      Molecular_name: F49B2.6
        F49B2.6.1
        CE40456
      Other_name: Y105E8A.a Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_F49B2.6 Accession_evidence: NDB BX284601
      Public_name: F49B2.6
    DB_info: Database: AceView gene 1O931
        WormQTL gene WBGene00009865
        WormFlux gene WBGene00009865
        NDB locus_tag CELE_F49B2.6
        Panther gene CAEEL|WormBase=WBGene00009865|UniProtKB=G5EGH4
          family PTHR11533
        NCBI gene 173297
        RefSeq protein NM_061102.5
        TrEMBL UniProtAcc G5EGH4
        UniProt_GCRP UniProtAcc G5EGH4
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (210)
    Strain: WBStrain00055195
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00030477 Caenorhabditis briggsae From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00060876 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00147013 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00157724 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00191813 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00144430 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00157991 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00154503 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00150184 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00190491 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00183208 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00135289 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00183999 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00126008 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00132166 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00126499 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00071953 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00065082 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00054961 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00066191 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00059046 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00137969 Caenorhabditis japonica From_analysis: TreeFam
      CBOVI.g10254 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g8662 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g5858 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g8294 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g13417 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g14236 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g1830 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g3354 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g12375 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g4671 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-F49B2.6 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g19063 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00271.g8397 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_09150 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_001470 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g05928 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g17479 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10007500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g2900 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00260320 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00287084 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301771 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0038135 Drosophila melanogaster From_analysis: Hieranoid
            Panther
            SonicParanoid
      FB:FBgn0052473 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      FB:FBgn0039064 Drosophila melanogaster From_analysis: OrthoFinder
            Panther
            PhylomeDB
      FB:FBgn0039640 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OMA
            Panther
            SonicParanoid
      FB:FBgn0039656 Drosophila melanogaster From_analysis: Hieranoid
            OMA
            Panther
      FB:FBgn0263236 Drosophila melanogaster From_analysis: Hieranoid
            OMA
            Panther
      ZFIN:ZDB-GENE-030131-1253 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-030131-1534 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040426-934 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050309-218 Danio rerio From_analysis: Hieranoid
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-091113-7 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-080402-6 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:500 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Panther
      HGNC:6656 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:18173 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:29499 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1933403 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2387123 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
            SonicParanoid
      RGD:708542 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      RGD:621752 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
    Paralog (13)
    Structured_description: Automated_description: Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including severe acute respiratory syndrome; severe pre-eclampsia; and uterine disease (multiple). Is an ortholog of human ERAP1 (endoplasmic reticulum aminopeptidase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:2871 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18173)
      DOID:2945 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:500)
      DOID:2893 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18173)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6656)
      DOID:13129 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18173,HGNC:29499,HGNC:6656)
      DOID:127 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6656)
      DOID:4450 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6656)
      DOID:8488 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6656)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6656)
  Molecular_info: Corresponding_CDS: F49B2.6
    Corresponding_CDS_history: F49B2.6:wp165
    Corresponding_transcript: F49B2.6.1
    Other_sequence: RSC03442_1
      ACC27304_1
      Oden_isotig21442
      Dviv_isotig05052
      JI166885.1
      Dviv_isotig05053
      JO471077.1
      RS09292
    Associated_feature (15)
  Experimental_info: RNAi_result: WBRNAi00047794 Inferred_automatically: RNAi_primary
      WBRNAi00003723 Inferred_automatically: RNAi_primary
      WBRNAi00026540 Inferred_automatically: RNAi_primary
      WBRNAi00026541 Inferred_automatically: RNAi_primary
      WBRNAi00004468 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028980
      Expr1151628
      Expr2003904
      Expr2022126
    Microarray_results (26)
    Expression_cluster (131)
    Interaction: WBInteraction000460229
  Map_info: Positive: Positive_clone: F49B2 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I 24.4129
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene