This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
Enriched in several structures, including Z1.p; intestine; male distal tip cell; neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including methylmercuric chloride; bisphenol A; and sesamin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; FTH domain; HTH domain in Mos1 transposase; F-box domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.