WormBase Tree Display for Gene: WBGene00009732

WBGene00009732 SMap: S_parent: Sequence: F45G2
  Identity: Version: 2
    Name: CGC_name: cope-1 Person_evidence: WBPerson3188
      Sequence_name: F45G2.4
      Molecular_name: F45G2.4
        F45G2.4.1
        CE16047
      Other_name: CELE_F45G2.4 Accession_evidence: NDB BX284603
      Public_name: cope-1
    DB_info: Database: AceView gene 3O517
        WormQTL gene WBGene00009732
        WormFlux gene WBGene00009732
        NDB locus_tag CELE_F45G2.4
        Panther gene CAEEL|WormBase=WBGene00009732|UniProtKB=O62246
          family PTHR10805
        NCBI gene 176766
        RefSeq protein NM_067370.7
        SwissProt UniProtAcc O62246
        TREEFAM TREEFAM_ID TF313390
        UniProt_GCRP UniProtAcc O62246
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 08 Aug 2013 16:41:57 WBPerson2970 Name_change: CGC_name: cope-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cope
    Allele (23)
    Strain: WBStrain00049328
    RNASeq_FPKM (74)
    GO_annotation (15)
    Contained_in_operon: CEOP3788
    Ortholog (38)
    Structured_description: Concise_description: F45G2.4 encodes an epsilon subunit of the coatomer (COPI) complex; in mass RNAi assays, F45G2.4 is required for larval viability, proper locomotion, and properly rapid growth. Paper_evidence: WBPaper00006395
            WBPaper00012764
            WBPaper00012858
            WBPaper00012863
            WBPaper00012889
            WBPaper00013106
            WBPaper00013627
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable structural molecule activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Located in mitochondrion. Is an ortholog of human COPE (COPI coat complex subunit epsilon). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F45G2.4
    Corresponding_transcript: F45G2.4.1
    Other_sequence: CJC04570_1
      CJC01076_1
      CBC04683_1
    Associated_feature: WBsf645715
      WBsf226008
  Experimental_info: RNAi_result: WBRNAi00047437 Inferred_automatically: RNAi_primary
      WBRNAi00025518 Inferred_automatically: RNAi_primary
      WBRNAi00006013 Inferred_automatically: RNAi_primary
      WBRNAi00032323 Inferred_automatically: RNAi_primary
      WBRNAi00027344 Inferred_automatically: RNAi_primary
      WBRNAi00025517 Inferred_automatically: RNAi_primary
      WBRNAi00015042 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9522
      Expr1019686
      Expr1034258
      Expr1151278
      Expr2010459
      Expr2028699
    Drives_construct: WBCnstr00031958
    Construct_product: WBCnstr00014087
      WBCnstr00031958
    Microarray_results (21)
    Expression_cluster: WBPaper00028451:Low_abundance_spermatogenesis_enriched
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00032528:L3_enriched
      WBPaper00037047:insoluble_protein
      WBPaper00038289:oocyte_protein
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00044736:flat_dev_expression
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00050015:ifg-1(RNAi)_downregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051311:VGLN-1-interacting
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00058691:WDR-5.1_interacting_protein
      WBPaper00059174:MEG-3_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059605:MUT-16_interacting
      WBPaper00061340:GLR
      WBPaper00061340:hmc_and_homolog
      WBPaper00061340:hmc_homolog
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061466:nath-10(icb102)_downregulated
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:klp-12-F10C2.5
      WBPaper00061651:Coelomocyte_enriched
      WBPaper00061651:VC_4_5_enriched
      WBPaper00061651:VC_enriched
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064716:paraquat_upregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      cgc4386_cluster_4_5
      cgc4489_group_8
      WBPaper00025032:cluster_80
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00032948:FedUp
      WBPaper00035905:FBF-1_Associated
      WBPaper00040858:eQTL_regulated_old
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(143_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (30)
  Map_info: Map: III Position: 21.2136
    Positive: Positive_clone: F45G2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038444
    WBPaper00038491
    WBPaper00041771
    WBPaper00049828
    WBPaper00055090
    WBPaper00065275
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene