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WormBase Tree Display for Gene: WBGene00008829

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Name Class

WBGene00008829SMapS_parentSequenceF14H3
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classcyp
Allele (140)
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (56)
Paralog (45)
Structured_descriptionAutomated_descriptionPredicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2E1 (cytochrome P450 family 2 subfamily E member 1); and CYP2S1 (cytochrome P450 family 2 subfamily S member 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (30)
Molecular_infoCorresponding_CDSF14H3.10
Corresponding_transcriptF14H3.10.1
Associated_feature (5)
Experimental_infoRNAi_resultWBRNAi00092690Inferred_automaticallyRNAi_primary
WBRNAi00044650Inferred_automaticallyRNAi_primary
WBRNAi00114407Inferred_automaticallyRNAi_primary
WBRNAi00030966Inferred_automaticallyRNAi_primary
WBRNAi00114406Inferred_automaticallyRNAi_primary
WBRNAi00013318Inferred_automaticallyRNAi_primary
Expr_patternExpr1010619
Expr1148623
Expr2010741
Expr2028977
Drives_constructWBCnstr00018363
WBCnstr00032652
Construct_productWBCnstr00032652
Microarray_results (16)
Expression_cluster (151)
Interaction (18)
Map_infoMapVPosition9.44886Error0.003556
PositivePositive_cloneF14H3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00043063
WBPaper00044018
WBPaper00062515
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene