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WormBase Tree Display for Gene: WBGene00008781

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Name Class

WBGene00008781SMapS_parentSequenceF14B4
IdentityVersion2
NameCGC_namerpoa-2Person_evidenceWBPerson10054
Sequence_nameF14B4.3
Molecular_nameF14B4.3
F14B4.3.1
CE05629
Other_nameCELE_F14B4.3Accession_evidenceNDBBX284601
Public_namerpoa-2
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
228 Sep 2012 14:29:00WBPerson2970Name_changeCGC_namerpoa-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrpoa
Allele (63)
StrainWBStrain00002697
WBStrain00037291
WBStrain00040526
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (42)
ParalogWBGene00016140Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00017300Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and ribonucleoside binding activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in transcription by RNA polymerase I. Located in nucleolus. Expressed in several structures, including intestine. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Is an ortholog of human POLR1B (RNA polymerase I subunit B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080792Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:20454)
Molecular_infoCorresponding_CDSF14B4.3
Corresponding_transcriptF14B4.3.1
Other_sequence (43)
Associated_featureWBsf649458
WBsf664699
WBsf664700
WBsf664701
WBsf984638
WBsf984639
WBsf1010341
WBsf1010342
WBsf220066
WBsf220067
Experimental_infoRNAi_result (24)
Expr_patternChronogram573
Expr5754
Expr11399
Expr1015934
Expr1033834
Expr1148526
Expr2015500
Expr2033735
Drives_constructWBCnstr00003239
WBCnstr00018640
WBCnstr00018641
WBCnstr00032692
Construct_productWBCnstr00018640
WBCnstr00018641
WBCnstr00018642
WBCnstr00032692
Regulate_expr_clusterWBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
WBPaper00065945:epidermis-rpoa-2(-)_downregulated_transcript
WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
WBPaper00065945:epidermis-rpoa-2(-)_upregulated_transcript
WBPaper00065945:global-rpoa-2(-)_downregulated_transcript
WBPaper00065945:global-rpoa-2(-)_upregulated_transcript
Microarray_results (21)
Expression_cluster (148)
Interaction (326)
Map_infoMapIPosition3.72796
PositivePositive_cloneF14B4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00029435
WBPaper00038491
WBPaper00044530
WBPaper00046427
WBPaper00055090
WBPaper00064339
WBPaper00065012
WBPaper00065945
WBPaper00065957
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene