WormBase Tree Display for Gene: WBGene00008439

WBGene00008439 SMap: S_parent: Sequence: DY3
  Identity: Version: 2
    Name (5)
    DB_info: Database: AceView gene 1J356
        WormQTL gene WBGene00008439
        WormFlux gene WBGene00008439
        NDB locus_tag CELE_DY3.6
        Panther gene CAEEL|WormBase=WBGene00008439|UniProtKB=O45323
          family PTHR13123
        NCBI gene 183975
        RefSeq protein NM_059975.5
        TREEFAM TREEFAM_ID TF313070
        TrEMBL UniProtAcc O45323
        UniProt_GCRP UniProtAcc O45323
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 22 Dec 2004 08:53:54 WBPerson2970 Name_change: CGC_name: mfb-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mfb
    Allele (70)
    Strain: WBStrain00002459
      WBStrain00002900
      WBStrain00035998
    RNASeq_FPKM (74)
    GO_annotation: 00034241
      00034242
      00034243
      00034244
      00034245
      00034246
    Ortholog: WBGene00060002 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00033326 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00142384 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00124453 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00190281 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00232873 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g9186 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3892 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g10139 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g1591 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g17577 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g7736 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g5530 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g21298 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g29924 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g3986 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g24244 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00043.g2355 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-mfb-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g20538 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01411.g20757 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_05077 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002528 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g06278 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g11216 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10124110 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1673 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00237454 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00304740 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00262700 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00294490 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0036196 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040426-1040 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040801-19 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:13596 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:16731 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1914072 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1914981 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:620373 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1359105 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Automated_description: Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm and nucleus. Predicted to be part of SCF ubiquitin ligase complex. Expressed in several structures, including head; hypodermal cell; tail; touch receptor neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Is an ortholog of human FBXO25 (F-box protein 25) and FBXO32 (F-box protein 32). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:14557 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16731)
  Molecular_info: Corresponding_CDS: DY3.6
    Corresponding_transcript: DY3.6.1
    Other_sequence (99)
    Associated_feature: WBsf649419
      WBsf984505
      WBsf984506
      WBsf1010275
      WBsf219983
  Experimental_info: RNAi_result: WBRNAi00060999 Inferred_automatically: RNAi_primary
      WBRNAi00116913 Inferred_automatically: RNAi_primary
      WBRNAi00030444 Inferred_automatically: RNAi_primary
      WBRNAi00060998 Inferred_automatically: RNAi_primary
      WBRNAi00113747 Inferred_automatically: RNAi_primary
      WBRNAi00060997 Inferred_automatically: RNAi_primary
      WBRNAi00043553 Inferred_automatically: RNAi_primary
      WBRNAi00061000 Inferred_automatically: RNAi_primary
      WBRNAi00113743 Inferred_automatically: RNAi_primary
    Expr_pattern (12)
    Drives_construct: WBCnstr00003056
      WBCnstr00004524
      WBCnstr00011153
      WBCnstr00020326
    Construct_product: WBCnstr00011153
    Microarray_results (18)
    Expression_cluster (239)
    Interaction (18)
  Map_info: Map: I Position: 3.11369 Error: 0.005753
    Positive: Positive_clone: DY3 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4889
        4741
    Pseudo_map_position
  Reference: WBPaper00012854
    WBPaper00024548
    WBPaper00038491
    WBPaper00043086
    WBPaper00046423
    WBPaper00055090
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene