WormBase Tree Display for Gene: WBGene00008273
expand all nodes | collapse all nodes | view schema
| WBGene00008273 | SMap | S_parent | Sequence | C53B4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | Sequence_name | C53B4.3 | |||||||
| Molecular_name | C53B4.3 | ||||||||
| C53B4.3.1 | |||||||||
| CE37333 | |||||||||
| C53B4.3.2 | |||||||||
| Other_name | CELE_C53B4.3 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | C53B4.3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele (33) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00062322 | ||||||||
| 00062323 | |||||||||
| 00062324 | |||||||||
| 00062325 | |||||||||
| 00116215 | |||||||||
| 00116216 | |||||||||
| Ortholog (34) | |||||||||
| Structured_description | Concise_description | C53B4.3 is orthologous to the human gene, Solute Carrier Family 22 (Organic Cation Transporter), Member 18, referred to as SLC22A18; C53B4.3 is expressed in body wall muscle based on large-scale GFP studies. | Paper_evidence | WBPaper00038444 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 25 May 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in nucleus. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple) and breast cancer. Is an ortholog of human SLC22A18 (solute carrier family 22 member 18). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10964) | ||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10964) | ||||||
| DOID:234 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10964) | ||||||
| DOID:4914 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10964) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10964) | ||||||
| Disease_relevance | The human ortholog of elegans C53B4.3, SLC22A18 (Solute Carrier Family 22 (Organic Cation Transporter), Member 18), belongs to the family of polyspecific organic-cation transporters located at basolateral and apical surfaces of renal epithelial cells; mutations in SLC22A18/SLC22A1L are associated with several neoplasms including somatic breast cancer, lung cancer, and Rhabdomyosarcoma (a malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle). | Homo sapiens | Accession_evidence | OMIM | 114480 | ||||
| 211980 | |||||||||
| 268210 | |||||||||
| 602631 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 25 May 2012 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C53B4.3 | |||||||
| Corresponding_CDS_history | C53B4.3:wp47 | ||||||||
| C53B4.3:wp131 | |||||||||
| Corresponding_transcript | C53B4.3.1 | ||||||||
| C53B4.3.2 | |||||||||
| Other_sequence (16) | |||||||||
| Associated_feature | WBsf652029 | ||||||||
| WBsf652030 | |||||||||
| WBsf997327 | |||||||||
| WBsf230493 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00012342 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00043069 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001508 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00081135 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9497 | ||||||||
| Expr1023320 | |||||||||
| Expr1147034 | |||||||||
| Expr2001883 | |||||||||
| Expr2020109 | |||||||||
| Drives_construct | WBCnstr00033094 | ||||||||
| Construct_product | WBCnstr00014062 | ||||||||
| WBCnstr00033094 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (133) | |||||||||
| Interaction | WBInteraction000175081 | ||||||||
| Map_info | Positive | Positive_clone | C53B4 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | IV | 3.99993 | |||||||
| Reference | WBPaper00034662 | ||||||||
| WBPaper00038444 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
