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WormBase Tree Display for Gene: WBGene00008149

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Name Class

WBGene00008149SMapS_parentSequenceC47E12
IdentityVersion2
NameCGC_namepyp-1Person_evidenceWBPerson756
WBPerson268
Sequence_nameC47E12.4
Molecular_nameC47E12.4a
C47E12.4a.1
CE33767
C47E12.4c
CE48296
C47E12.4d
CE05448
C47E12.4c.1
C47E12.4d.1
Other_nameCELE_C47E12.4Accession_evidenceNDBBX284604
Public_namepyp-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
209 Sep 2005 11:08:45WBPerson2970Name_changeCGC_namepyp-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpyp
Allele (38)
StrainWBStrain00027494
RNASeq_FPKM (74)
GO_annotation (16)
Contained_in_operonCEOP4348
Ortholog (49)
Structured_descriptionConcise_descriptionpyp-1 encodes, by alternative splicing, three isoforms of an inorganic pyrophosphatase required for embryonic and larval viability, intestinal function, and distal tip cell migration; PYP-1 is catalytically active in vitro, and is expressed in neurons, intestine, and coelomocytes; PYP-1 is orthologous to Drosophila NURF-38, and to human PPA1 (OMIM:179030) and PPA2; by orthology with NURF-38, PYP-1 is also predicted to participate in nucleosome remodelling.Paper_evidenceWBPaper00027681
WBPaper00028783
WBPaper00031169
WBPaper00031236
Curator_confirmedWBPerson567
Date_last_updated26 Nov 2007 00:00:00
Automated_descriptionPredicted to enable inorganic diphosphate phosphatase activity. Involved in innate immune response. Located in neuron projection and vacuole. Expressed in coelomocyte and neurons. Is an ortholog of human PPA1 (inorganic pyrophosphatase 1) and PPA2 (inorganic pyrophosphatase 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC47E12.4a
C47E12.4c
C47E12.4d
Corresponding_CDS_historyC47E12.4:wp99
C47E12.4b:wp236
C47E12.4b:wp261
C47E12.4c:wp236
Corresponding_transcriptC47E12.4a.1
C47E12.4c.1
C47E12.4d.1
Other_sequence (133)
Associated_feature (11)
Experimental_infoRNAi_result (19)
Expr_patternExpr7807
Expr1020480
Expr1033540
Expr1146667
Expr2015205
Expr2033439
Drives_constructWBCnstr00012939
WBCnstr00033204
Construct_productWBCnstr00012939
WBCnstr00033204
AntibodyWBAntibody00001321
Microarray_results (41)
Expression_cluster (145)
Interaction (81)
Map_infoMapIVPosition4.46234Error0.00085
PositivePositive_cloneC47E12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene