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WormBase Tree Display for Gene: WBGene00007711

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Name Class

WBGene00007711SMapS_parentSequenceC25A1
IdentityVersion2
NameCGC_namelid-1Person_evidenceWBPerson8252
Sequence_nameC25A1.12
Molecular_name (12)
Other_nameCELE_C25A1.12Accession_evidenceNDBBX284601
Public_namelid-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
202 Sep 2013 15:55:36WBPerson2970Name_changeCGC_namelid-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlid
Allele (31)
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (41)
Paralog (14)
Structured_descriptionAutomated_descriptionPredicted to enable carboxylic ester hydrolase activity and lysophosphatidic acid acyltransferase activity. Predicted to be involved in lipid homeostasis and phosphatidic acid biosynthetic process. Located in lipid droplet. Expressed in intestinal cell. Used to study Chanarin-Dorfman syndrome. Human ortholog(s) of this gene implicated in Chanarin-Dorfman syndrome; autosomal recessive congenital ichthyosis 1; and colon adenocarcinoma. Is an ortholog of human ABHD4 (abhydrolase domain containing 4, N-acyl phospholipase B) and ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:0050729Homo sapiensPaper_evidenceWBPaper00060484
Curator_confirmedWBPerson324
Date_last_updated17 May 2022 00:00:00
Potential_modelDOID:0060656Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21396)
DOID:234Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21396)
DOID:0050729Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21396)
Models_disease_assertedWBDOannot00001198
Molecular_infoCorresponding_CDSC25A1.12a
C25A1.12b
C25A1.12c
C25A1.12d
Corresponding_CDS_historyC25A1.12:wp185
Corresponding_transcriptC25A1.12a.1
C25A1.12b.1
C25A1.12c.1
C25A1.12d.1
Other_sequence (60)
Associated_featureWBsf649558
WBsf649559
WBsf649560
WBsf664845
Experimental_infoRNAi_resultWBRNAi00116501Inferred_automaticallyRNAi_primary
WBRNAi00003007Inferred_automaticallyRNAi_primary
WBRNAi00102890Inferred_automaticallyRNAi_primary
WBRNAi00102004Inferred_automaticallyRNAi_primary
WBRNAi00102896Inferred_automaticallyRNAi_primary
WBRNAi00102899Inferred_automaticallyRNAi_primary
WBRNAi00102901Inferred_automaticallyRNAi_primary
WBRNAi00102891Inferred_automaticallyRNAi_primary
WBRNAi00041139Inferred_automaticallyRNAi_primary
Expr_patternExpr12051
Expr1025827
Expr1033340
Expr1145171
Expr2013148
Expr2031380
Construct_productWBCnstr00020138
Microarray_results (23)
Expression_cluster (104)
Interaction (21)
WBProcessWBbiopr:00000121
Map_infoMapIPosition4.73535
PositivePositive_cloneC25A1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00045710
WBPaper00047712
WBPaper00055090
WBPaper00060484
WBPaper00064339
WBPaper00066161
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene