WormBase Tree Display for Gene: WBGene00007443
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| WBGene00007443 | SMap | S_parent | Sequence | C08F8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pfd-1 | Person_evidence | WBPerson2136 | |||||
| WBPerson3663 | |||||||||
| Sequence_name | C08F8.1 | ||||||||
| Molecular_name | C08F8.1a | ||||||||
| C08F8.1a.1 | |||||||||
| CE05248 | |||||||||
| C08F8.1b | |||||||||
| CE45776 | |||||||||
| C08F8.1b.1 | |||||||||
| Other_name | CELE_C08F8.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | pfd-1 | ||||||||
| DB_info | Database | AceView | gene | 4L915 | |||||
| WormQTL | gene | WBGene00007443 | |||||||
| WormFlux | gene | WBGene00007443 | |||||||
| NDB | locus_tag | CELE_C08F8.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00007443|UniProtKB=Q17827 | |||||||
| family | PTHR20903 | ||||||||
| NCBI | gene | 178021 | |||||||
| RefSeq | protein | NM_001268612.4 | |||||||
| NM_001268611.4 | |||||||||
| SwissProt | UniProtAcc | Q17827 | |||||||
| TREEFAM | TREEFAM_ID | TF106490 | |||||||
| UniProt_GCRP | UniProtAcc | Q17827 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 02 Aug 2006 11:39:27 | WBPerson2970 | Name_change | CGC_name | pfd-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pfd | ||||||||
| Allele (15) | |||||||||
| Strain | WBStrain00027643 | ||||||||
| WBStrain00027644 | |||||||||
| WBStrain00002703 | |||||||||
| WBStrain00036248 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Contained_in_operon | CEOP4420 | ||||||||
| Ortholog (29) | |||||||||
| Structured_description | Concise_description | pfd-1 encodes a putative prefoldin subunit 1, orthologous to human PFDN1 (OMIM:604897), that is required for normal microtubule nucleation and growth, embryonic viability, distal tip cell (DTC) migration, and locomotion; PFD-1 is expressed cytoplasmically in most, if not all, tissues; pfd-1(RNAi) animals have sterile progeny and are uncoordinated, and pfd-1(RNAi) embryos show a reduced microtubule growth rate; pfd-1(gk526) or escaper pfd-1(RNAi) hermaphrodites exhibit detective DTC migration. | Paper_evidence | WBPaper00004651 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00006395 | |||||||||
| WBPaper00024497 | |||||||||
| WBPaper00026660 | |||||||||
| WBPaper00031309 | |||||||||
| WBPaper00031362 | |||||||||
| WBPaper00031363 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 14 Jan 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein folding chaperone and unfolded protein binding activity. Involved in gonad development. Located in cytoplasm. Expressed in head muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human PFDN1 (prefoldin subunit 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C08F8.1a | |||||||
| C08F8.1b | |||||||||
| Corresponding_transcript | C08F8.1a.1 | ||||||||
| C08F8.1b.1 | |||||||||
| Other_sequence (24) | |||||||||
| Associated_feature | WBsf646357 | ||||||||
| WBsf229107 | |||||||||
| Experimental_info | RNAi_result (34) | ||||||||
| Expr_pattern | Expr5210 | ||||||||
| Expr7839 | |||||||||
| Expr7844 | |||||||||
| Expr9564 | |||||||||
| Expr1028881 | |||||||||
| Expr1033205 | |||||||||
| Expr1144198 | |||||||||
| Expr2014841 | |||||||||
| Expr2033076 | |||||||||
| Drives_construct | WBCnstr00001362 | ||||||||
| WBCnstr00001364 | |||||||||
| WBCnstr00003245 | |||||||||
| WBCnstr00033735 | |||||||||
| Construct_product | WBCnstr00033735 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (83) | |||||||||
| Interaction (26) | |||||||||
| Map_info | Map | IV | Position | 4.91006 | Error | 0.00115 | |||
| Positive | Positive_clone | C08F8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031309 | ||||||||
| WBPaper00038444 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
