WormBase Tree Display for Gene: WBGene00007143

WBGene00007143 SMap: S_parent: Sequence: B0334
  Identity: Version: 2
    Name: CGC_name: hacl-1 Person_evidence: WBPerson7188
          Author_evidence: Bennett Fox
      Sequence_name: B0334.3
      Molecular_name: B0334.3a
        B0334.3a.1
        CE19658
        B0334.3b
        CE46937
        B0334.3b.1
      Other_name: CELE_B0334.3 Accession_evidence: NDB BX284602
      Public_name: hacl-1
    DB_info: Database: AceView gene 2L780
        WormQTL gene WBGene00007143
        WormFlux gene WBGene00007143
        NDB locus_tag CELE_B0334.3
        Panther gene CAEEL|WormBase=WBGene00007143|UniProtKB=Q17474
          family PTHR43710
        NCBI gene 174758
        RefSeq protein NM_064053.6
            NM_001393195.1
        TREEFAM TREEFAM_ID TF105690
        TrEMBL UniProtAcc Q17474
            Q17475
        UniProt_GCRP UniProtAcc Q17474
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:47 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 14 Jun 2021 10:43:28 WBPerson1983 Name_change: CGC_name: hacl-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: hacl
    Allele (59)
    RNASeq_FPKM (74)
    GO_annotation: 00058250
      00058251
      00058252
      00058253
      00115366
      00115367
      00115368
    Contained_in_operon: CEOP2544
    Ortholog (41)
    Paralog: WBGene00020831 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable thiamine pyrophosphate binding activity. Predicted to be involved in fatty acid alpha-oxidation. Predicted to be located in peroxisome. Is an ortholog of human HACL1 (2-hydroxyacyl-CoA lyase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: B0334.3a
      B0334.3b
    Corresponding_CDS_history: B0334.3b:wp229
    Corresponding_transcript: B0334.3a.1
      B0334.3b.1
    Other_sequence (30)
    Associated_feature: WBsf650584
      WBsf650585
      WBsf665275
      WBsf666144
      WBsf666145
      WBsf666146
  Experimental_info: RNAi_result: WBRNAi00090933 Inferred_automatically: RNAi_primary
      WBRNAi00038929 Inferred_automatically: RNAi_primary
      WBRNAi00009705 Inferred_automatically: RNAi_primary
      WBRNAi00038928 Inferred_automatically: RNAi_primary
      WBRNAi00028088 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023868
      Expr1033074
      Expr1143113
      Expr2000142
      Expr2018360
    Drives_construct: WBCnstr00033967
    Construct_product: WBCnstr00033967
    Microarray_results (23)
    Expression_cluster: WBPaper00026640:Development_Group_I
      WBPaper00028451:Oogenic_protein
      WBPaper00032528:L3_enriched
      WBPaper00035963:S.aureus_8h_upregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00040134:nhr-49(RNAi)_regulated_protein
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046217:gas-1(fc21)_upregulated
      WBPaper00046303:P.aeruginosa_upregulated_protein
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051538:micro-gavity_downregulated_protein
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055969:electromagnetic-field_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00057254:MWCNT_downregulated_mRNA
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058801:ceh-60(lst466)_upregulated_protein
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060871:M.humicola-infection_24h_regulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061340:hyp4_hyp5_hyp6
      WBPaper00061340:hyp7_AB_lineage
      WBPaper00061340:Intestine
      WBPaper00061340:P_cell
      WBPaper00061527:dhs-28_22199-acs-14
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064315:mes-3(bn199)_downregulated_PGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      cgc4386_cluster_3_3
      cgc4489_group_24
      WBPaper00005124:testosterone_10-9M_regulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00034739:TreatmentAffectedGenes
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00037695:WC_5-day
      WBPaper00040963:Q50_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_C
    Interaction (29)
  Map_info: Map: II Position: 3.51255
    Positive: Positive_clone: B0334 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00041022
    WBPaper00055090
    WBPaper00062489
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene