WormBase Tree Display for Gene: WBGene00007135
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| WBGene00007135 | SMap | S_parent | Sequence | B0285 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 4 | |||||||
| Name | CGC_name | cdk-12 | Person_evidence | WBPerson313 | |||||
| WBPerson3232 | |||||||||
| WBPerson555 | |||||||||
| Sequence_name | B0285.1 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | cdtl-7 | Person_evidence | WBPerson3232 | ||||||
| WBPerson555 | |||||||||
| CELE_B0285.1 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | cdk-12 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:47 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 02 Mar 2009 11:15:07 | WBPerson9133 | Name_change | CGC_name | cdtl-7 | ||||
| 3 | 23 Nov 2012 14:00:52 | WBPerson2970 | Name_change | CGC_name | cdk-12 | ||||
| 4 | 10 Jun 2014 12:12:12 | WBPerson1983 | Event | Acquires_merge | WBGene00043080 | ||||
| Acquires_merge | WBGene00043080 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cdk | ||||||||
| Allele (122) | |||||||||
| Strain | WBStrain00003574 | ||||||||
| WBStrain00024046 | |||||||||
| WBStrain00024054 | |||||||||
| WBStrain00024069 | |||||||||
| WBStrain00024070 | |||||||||
| WBStrain00037602 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Ortholog (38) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Automated_description | Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in nematode larval development. Part of euchromatin. Expressed in several structures, including germ line and head. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; carcinoma (multiple); and congenital heart defects, dysmorphic facial features, and intellectual developmental disorder. Is an ortholog of human CDK13 (cyclin dependent kinase 13). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112247 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1733) | ||||
| DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:24224) | ||||||
| DOID:10286 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1733) | ||||||
| DOID:3717 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:24224) | ||||||
| DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1733) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1733,HGNC:24224) | ||||||
| DOID:1059 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1733) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1733) | ||||||
| Molecular_info | Corresponding_CDS | B0285.1a | |||||||
| B0285.1b | |||||||||
| B0285.1c | |||||||||
| Corresponding_CDS_history | B0285.1:wp23 | ||||||||
| B0285.1:wp83 | |||||||||
| Corresponding_transcript | B0285.1a.1 | ||||||||
| B0285.1a.2 | |||||||||
| B0285.1b.1 | |||||||||
| B0285.1b.2 | |||||||||
| B0285.1c.1 | |||||||||
| B0285.1c.2 | |||||||||
| Other_sequence (19) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (56) | ||||||||
| Expr_pattern | Chronogram501 | ||||||||
| Expr5038 | |||||||||
| Expr11660 | |||||||||
| Expr1020850 | |||||||||
| Expr1033070 | |||||||||
| Expr1143059 | |||||||||
| Expr2009808 | |||||||||
| Expr2028049 | |||||||||
| Drives_construct | WBCnstr00004026 | ||||||||
| WBCnstr00033974 | |||||||||
| Construct_product | WBCnstr00019156 | ||||||||
| WBCnstr00019285 | |||||||||
| WBCnstr00019286 | |||||||||
| WBCnstr00019287 | |||||||||
| WBCnstr00033974 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (96) | |||||||||
| Interaction (92) | |||||||||
| Map_info | Map | III | Position | -3.18675 | Error | 0.000933 | |||
| Positive | Positive_clone | B0285 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027258 | ||||||||
| WBPaper00031224 | |||||||||
| WBPaper00032961 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00044000 | |||||||||
| WBPaper00047409 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060756 | |||||||||
| WBPaper00063946 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag. | |||||||||
| Method | Gene |
