WormBase Tree Display for Gene: WBGene00007006
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WBGene00007006 | Evidence | CGC_data_submission | ||||||
---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C10C6 | |||||
Identity | Version | 1 | ||||||
Name | CGC_name | npr-3 | Person_evidence | WBPerson42 | ||||
Sequence_name | C10C6.2 | |||||||
Molecular_name | C10C6.2 | |||||||
C10C6.2.1 | ||||||||
CE08056 | ||||||||
Other_name | flp15-R | |||||||
CELE_C10C6.2 | Accession_evidence | NDB | BX284604 | |||||
Public_name | npr-3 | |||||||
DB_info | Database | AceView | gene | 4M225 | ||||
WormQTL | gene | WBGene00007006 | ||||||
WormFlux | gene | WBGene00007006 | ||||||
NDB | locus_tag | CELE_C10C6.2 | ||||||
Panther | gene | CAEEL|WormBase=WBGene00007006|UniProtKB=P90745 | ||||||
family | PTHR24240 | |||||||
NCBI | gene | 182494 | ||||||
RefSeq | protein | NM_069761.4 | ||||||
TrEMBL | UniProtAcc | P90745 | ||||||
UniProt_GCRP | UniProtAcc | P90745 | ||||||
Species | Caenorhabditis elegans | |||||||
History | Version_change | 1 | 22 Apr 2004 16:09:48 | WBPerson1971 | Event | Created | ||
Status | Live | |||||||
Gene_info | Biotype | SO:0001217 | ||||||
Gene_class | npr | |||||||
Allele (35) | ||||||||
RNASeq_FPKM (74) | ||||||||
GO_annotation (13) | ||||||||
Ortholog (38) | ||||||||
Paralog (22) | ||||||||
Structured_description | Concise_description | C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory | Paper_evidence | WBPaper00006156 | ||||
Curator_confirmed | WBPerson567 | |||||||
Date_last_updated | 09 Aug 2004 00:00:00 | |||||||
Automated_description | Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to be located in membrane. Expressed in ventral cord neurons. Human ortholog(s) of this gene implicated in hypertension. Is an ortholog of human PRLHR (prolactin releasing hormone receptor). | Paper_evidence | WBPaper00065943 | |||||
Curator_confirmed | WBPerson324 | |||||||
WBPerson37462 | ||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||||
Disease_info | Potential_model | DOID:10763 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4464) | |||
Molecular_info (4) | ||||||||
Experimental_info | RNAi_result | WBRNAi00040290 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00028772 | Inferred_automatically | RNAi_primary | ||||||
WBRNAi00075423 | Inferred_automatically | RNAi_primary | ||||||
WBRNAi00010590 | Inferred_automatically | RNAi_primary | ||||||
WBRNAi00072930 | Inferred_automatically | RNAi_primary | ||||||
Expr_pattern | Expr2766 | |||||||
Expr1016827 | ||||||||
Expr1144363 | ||||||||
Expr2014423 | ||||||||
Expr2032664 | ||||||||
Drives_construct | WBCnstr00010940 | |||||||
WBCnstr00034044 | ||||||||
Construct_product | WBCnstr00010940 | |||||||
WBCnstr00034044 | ||||||||
Microarray_results (19) | ||||||||
Expression_cluster (110) | ||||||||
Interaction (63) | ||||||||
Map_info | Map | IV | Position | 4.98602 | Error | 0.001483 | ||
Positive | Positive_clone | C10C6 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
Mapping_data | Multi_point | 4832 | ||||||
4863 | ||||||||
5044 | ||||||||
Pseudo_map_position | ||||||||
Reference | WBPaper00006132 | |||||||
WBPaper00006156 | ||||||||
WBPaper00027520 | ||||||||
WBPaper00038491 | ||||||||
WBPaper00043908 | ||||||||
WBPaper00049732 | ||||||||
WBPaper00050768 | ||||||||
WBPaper00055090 | ||||||||
WBPaper00055865 | ||||||||
WBPaper00065946 | ||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |