WormBase Tree Display for Gene: WBGene00006948
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WBGene00006948 | SMap | S_parent | Sequence | F52E4 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | wrt-2 | Person_evidence | WBPerson83 | |||||
Sequence_name | F52E4.6 | ||||||||
Molecular_name | F52E4.6 | ||||||||
F52E4.6.1 | |||||||||
CE07273 | |||||||||
Other_name | CELE_F52E4.6 | Accession_evidence | NDB | BX284606 | |||||
Public_name | wrt-2 | ||||||||
DB_info | Database | AceView | gene | XD712 | |||||
WormQTL | gene | WBGene00006948 | |||||||
WormFlux | gene | WBGene00006948 | |||||||
NDB | locus_tag | CELE_F52E4.6 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00006948|UniProtKB=Q20677 | |||||||
family | PTHR46706 | ||||||||
NCBI | gene | 180597 | |||||||
RefSeq | protein | NM_076128.7 | |||||||
TREEFAM | TREEFAM_ID | TF316084 | |||||||
TrEMBL | UniProtAcc | Q20677 | |||||||
UniProt_GCRP | UniProtAcc | Q20677 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | wrt | ||||||||
Allele (28) | |||||||||
Strain | WBStrain00007244 | ||||||||
WBStrain00007245 | |||||||||
WBStrain00007246 | |||||||||
WBStrain00007914 | |||||||||
WBStrain00032807 | |||||||||
RNASeq_FPKM (74) | |||||||||
Ortholog (23) | |||||||||
Paralog (24) | |||||||||
Structured_description | Concise_description | wrt-2 encodes a hedgehog-like protein, with an N-terminal signalsequence, a Wart domain, and a C-terminal region of low-complexitysequence; WRT-2 is expressed in seam cells and hypodermal syncytia; theWart domain is predicted to form a cysteine-crosslinked protein involvedin intercellular signalling, and it has subtle similarity to theN-terminal Hedge domain of HEDGEHOG proteins; WRT-2 is weakly requiredfor normal molting; WRT-2 is also required for normal growth to fullsize and locomotion; all of these requirements may reflect commondefects in cholesterol-dependent hedgehog-like signalling or in vesicletrafficking; in two-hybrid assays, WRT-2 binds EYA-1, which may parallelthe derepression of Drosophila eyes absent by HEDGEHOG. | Paper_evidence | WBPaper00003717 | |||||
WBPaper00006332 | |||||||||
WBPaper00026841 | |||||||||
WBPaper00027263 | |||||||||
WBPaper00027697 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
Automated_description | Expressed in hypodermal cell and hypodermis. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F52E4.6 | |||||||
Corresponding_transcript | F52E4.6.1 | ||||||||
Other_sequence (41) | |||||||||
Associated_feature | WBsf653804 | ||||||||
WBsf653805 | |||||||||
WBsf1022564 | |||||||||
WBsf1022565 | |||||||||
WBsf1022566 | |||||||||
WBsf237135 | |||||||||
WBsf237136 | |||||||||
Experimental_info (8) | |||||||||
Map_info | Map | X | Position | -12.232 | Error | 0.019344 | |||
Positive | Positive_clone | F52E4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (13) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |